1970
A Study of the Renin-Angiotensin System in Patients with Severe Chronic Renal Insufficiency
Kotchen T, Knight E, Kashgarian M, Mulrow P. A Study of the Renin-Angiotensin System in Patients with Severe Chronic Renal Insufficiency. Nephron 1970, 7: 317-330. PMID: 4316656, DOI: 10.1159/000179832.Peer-Reviewed Original ResearchConceptsRenin activitySevere chronic renal insufficiencyChronic dialysis programRenin substrate levelsChronic renal insufficiencyPlasma renin activityMean arterial pressureRenin-angiotensin systemNormal plasma levelsMalignant hypertensionRenal insufficiencyRenin levelsOnly patientsArterial pressureBlood pressureUremic patientsDialysis programPlasma levelsUremic plasmaAutopsy specimensJG cellsBowie stainPatientsReninDialysis
1969
Physiologic studies in renal osteodystrophy treated by subtotal parathyroidectomy
Gill G, Pallotta J, Kashgarian M, Kessner D, Epstein F. Physiologic studies in renal osteodystrophy treated by subtotal parathyroidectomy. The American Journal Of Medicine 1969, 46: 930-940. PMID: 5797916, DOI: 10.1016/0002-9343(69)90095-3.Peer-Reviewed Original ResearchConceptsSubtotal parathyroidectomyParathyroid hormoneRenal osteodystrophyAbnormal renal handlingAdvanced renal insufficiencyOsteitis fibrosa cysticaRenal tubular reabsorptionRoentgenologic evidenceRenal insufficiencyFibrosa cysticaPreoperative levelsMetastatic calcificationUremic patientsTubular reabsorptionParathyroid tissueMedullary cystsRenal handlingPhysiologic studiesPatientsParathyroidectomyBone healingHormoneOsteodystrophyHypercalciuriaCystica