2008
Disruption of Myosin 1e Promotes Podocyte Injury
Krendel M, Kim SV, Willinger T, Wang T, Kashgarian M, Flavell RA, Mooseker MS. Disruption of Myosin 1e Promotes Podocyte Injury. Journal Of The American Society Of Nephrology 2008, 20: 86-94. PMID: 19005011, PMCID: PMC2615733, DOI: 10.1681/asn.2007111172.Peer-Reviewed Original ResearchConceptsChronic renal injuryNormal glomerular filtrationGlomerular basement membraneRenal injuryKidney inflammationPodocyte foot processesGlomerular diseasePodocyte injuryGlomerular filtrationRenal tissueFoot processesPodocyte functionBasement membraneInjuryUltrastructural levelDiseaseMiceType IProteinuriaInflammationKidneyImportant rolePodocytes
1977
SEQUENTIAL HISTOLOGIC CHANGES IN UNTREATED MESANGIALCAPILLARY GLOMERULONEPHRITIS (MCGN)
Siegel N, Kashgarian M. SEQUENTIAL HISTOLOGIC CHANGES IN UNTREATED MESANGIALCAPILLARY GLOMERULONEPHRITIS (MCGN). Pediatric Research 1977, 11: 557-557. DOI: 10.1203/00006450-197704000-01126.Peer-Reviewed Original ResearchInterstitial fibrosisMesangial sclerosisSubendothelial depositsSecond renal biopsyDiffuse mesangial proliferationHistologic improvementSteroid therapyImmunosuppressive agentsRenal biopsyInitial diagnosisMesangial proliferationPatientsSubepithelial depositsSequential histologicSclerosisBasement membraneFibrosisRecent dataSignificant changesProliferationProgressive changesGlomerulonephritisBiopsyHistologicTherapy
1971
Successful Treatment of Renal Failure in Goodpasture's Syndrome
Hayslett J, Berte J, Kashgarian M. Successful Treatment of Renal Failure in Goodpasture's Syndrome. JAMA Internal Medicine 1971, 127: 953-957. PMID: 5560872, DOI: 10.1001/archinte.1971.00310170161025.Peer-Reviewed Original ResearchConceptsGoodpasture's syndromeRenal failureYale-New Haven HospitalEvaluation of hemoptysisSymptoms of bronchospasmFurther renal deteriorationGlomerular basement membraneAcute bronchitisRenal deteriorationRenal insufficiencyPulmonary functionPulmonary tuberculosisSuccessful treatmentRapid progressionProlonged survivalImmune responseSerial studiesSyndromeWhite womenHemoptysisRecent evidenceBasement membraneComplete restorationWomenBronchospasm