1989
Metabolic alterations in proximal tubule suspensions obtained from ischemic kidneys
Gaudio K, Thulin G, Ardito T, Kashgarian M, Siegel N. Metabolic alterations in proximal tubule suspensions obtained from ischemic kidneys. American Journal Of Physiology 1989, 257: f383-f389. PMID: 2551186, DOI: 10.1152/ajprenal.1989.257.3.f383.Peer-Reviewed Original ResearchConceptsProximal tubule suspensionsIschemic injuryTubule suspensionsRenal artery ischemiaVivo ischemic injurySprague-Dawley ratsMin of reflowOxygen consumptionPresence of ouabainBasal O2 consumptionArtery ischemiaIschemic kidneyHistopathological appearanceMetabolic alterationsProximal tubulesControl levelsProtein 1
1982
Accelerated recovery of single nephron function by the postischemic infusion of ATP-MgCl2
Gaudio K, Taylor M, Chaudry I, Kashgarian M, Siegel N. Accelerated recovery of single nephron function by the postischemic infusion of ATP-MgCl2. Kidney International 1982, 22: 13-20. PMID: 7120752, DOI: 10.1038/ki.1982.126.Peer-Reviewed Original ResearchConceptsClearance of inulinSingle nephron functionATP-MgCl2Proximal tubular pressureNephron functionTubular pressureBeneficial effectsRenal artery ischemiaSaline-treated animalsSaline-treated ratsCourse of recoveryGroups of animalsPostischemic administrationArtery ischemiaPattern of recoveryCIN 1Postischemic infusionInitial insultInulin clearanceInitial improvementControl animalsMost epithelial cellsEnhanced recoveryWhole kidneyTubular fluid