Peripheral-to-central ratio of Guttae: validity and reliability of an objective method to characterize severity of Fuchs endothelial corneal dystrophy
Bajaj RP, Fliotsos MJ, Pradeep T, Eghrari AO. Peripheral-to-central ratio of Guttae: validity and reliability of an objective method to characterize severity of Fuchs endothelial corneal dystrophy. Graefe's Archive For Clinical And Experimental Ophthalmology 2020, 259: 685-690. PMID: 33128674, PMCID: PMC7904627, DOI: 10.1007/s00417-020-04985-1.Peer-Reviewed Original ResearchMeSH KeywordsEndothelium, CornealFuchs' Endothelial DystrophyHumansPilot ProjectsReproducibility of ResultsROC CurveSlit LampConceptsFuchs endothelial corneal dystrophyEndothelial corneal dystrophyCorneal dystrophySeverity scoreInter-rater reliabilitySevere diseaseClinical severity scoreCentral ratioGood inter-rater reliabilityAffected eyeFuchs' dystrophyMethodsFifteen patientsClinical severitySevere casesIndependent gradersPilot studyRatio cutoffSeverityDystrophyGuttaeDiseaseBaselineScoresBottom 4Objective method