2022
Baltimore pediatric ocular trauma study: Health disparities and outcomes in pediatric and adolescent open globe trauma
Chen V, Pharr C, Junn S, Kraus C, Fliotsos M, Park H, Alexander J, Woreta F, Carey G, Levin M. Baltimore pediatric ocular trauma study: Health disparities and outcomes in pediatric and adolescent open globe trauma. Injury 2022, 54: 533-539. PMID: 36384857, DOI: 10.1016/j.injury.2022.11.013.Peer-Reviewed Original ResearchConceptsTraumatic open globe injuriesOpen globe injuriesPediatric ocular trauma scoreFinal visual acuityGlobe injuriesVisual acuityUveal prolapseBlunt traumaHispanic patientsBlack patientsYounger ageOpen globe traumaResults Eighty patientsOcular Trauma ScoreRetrospective chart reviewSerious ocular injuriesMechanism of injuryJohns Hopkins HospitalMaryland Medical CenterEighty patientsInitial presentingChart reviewGlobe traumaVisual outcomeOcular injuriesDescemet membrane endothelial keratoplasty in eyes with COL8A2-associated corneal dystrophy
Dzhaber D, Fliotsos MJ, Abousy M, Kancherla S, Siadati S, Eberhart CG, Gottsch JD, Eghrari AO. Descemet membrane endothelial keratoplasty in eyes with COL8A2-associated corneal dystrophy. American Journal Of Ophthalmology Case Reports 2022, 26: 101544. PMID: 35540705, PMCID: PMC9079234, DOI: 10.1016/j.ajoc.2022.101544.Peer-Reviewed Original ResearchDescemet membrane endothelial keratoplastyCentral corneal thicknessEndothelial keratoplastyVisual acuityCorneal thicknessCorneal dystrophyPostoperative central corneal thicknessFirst postoperative yearTertiary academic centerExcellent visual acuityDecades of lifeCorneal endothelial dystrophyAnterior corneal changesPostoperative yearBullous keratopathyCorneal changesCorneal edemaManifest refractionThin corneasCorneal hazeChronic oedemaSpherical equivalentRefractive errorRefractive shiftEndothelial dystrophyGlobal Current Practice Patterns for the Management of Exogenous Endophthalmitis: A Survey by the American Society of Ophthalmic Trauma
Wakabayashi T, Miller SC, Patel SN, Fliotsos MJ, Justin GA, Agrawal R, Chen A, Hoskin AK, Blanch R, Cavuoto K, Meeralakshmi P, Ascarza A, Chen RWS, Colyer M, Woreta FA, Yonekawa Y. Global Current Practice Patterns for the Management of Exogenous Endophthalmitis: A Survey by the American Society of Ophthalmic Trauma. Current Eye Research 2022, 47: 802-808. PMID: 34886727, DOI: 10.1080/02713683.2021.2016857.Peer-Reviewed Original ResearchConceptsExogenous endophthalmitisGlobal practice patternsPractice patternsOral antibioticsSurgical indicationsOphthalmic traumaCurrent practice patternsEvidence-based guidelinesCross-sectional studyAmerican SocietyInternational GlobeIntravitreal steroidsIntravitreal vancomycinMedical therapyPreferred agentVisual acuityVitreous tapStudy groupEndophthalmitisTrauma SocietyUniform guidancePatientsTraumaAntibioticsIndicationsCorneal Edema and Keratoplasty: Risk Factors in Eyes With Previous Glaucoma Drainage Devices
Beatson B, Wang J, Boland MV, Ramulu P, Schein O, Fliotsos MJ, Sulewski ME, Srikumaran D. Corneal Edema and Keratoplasty: Risk Factors in Eyes With Previous Glaucoma Drainage Devices. American Journal Of Ophthalmology 2022, 238: 27-35. PMID: 34995525, PMCID: PMC9149105, DOI: 10.1016/j.ajo.2021.12.017.Peer-Reviewed Original ResearchConceptsCorneal decompensationRisk factorsPostoperative complicationsGDD implantationVisual acuityGlaucoma drainage device implantationRetrospective case-control studyKaplan-Meier survival analysisJohns Hopkins Wilmer Eye InstituteFinal visual outcomePostoperative corneal decompensationTube-cornea touchDrainage device implantationIridocorneal endothelial syndromeWilmer Eye InstituteSignificant risk factorsCase-control studyProportional hazards modelGlaucoma drainage deviceUnderwent keratoplastyEndothelial syndromeVisual outcomeCorneal edemaEye InstituteDevice implantation
2020
Corneal thinning and cornea guttata in patients with mutations in TGFB2
Eghrari AO, Rasooly MM, Fliotsos MJ, Kinard J, Odozor O, Cunningham D, Bishop RJ, Guerrerio AL, Frischmeyer-Guerrerio PA. Corneal thinning and cornea guttata in patients with mutations in TGFB2. Canadian Journal Of Ophthalmology 2020, 55: 336-341. PMID: 32307099, PMCID: PMC8049842, DOI: 10.1016/j.jcjo.2020.03.007.Peer-Reviewed Original ResearchConceptsLoeys-Dietz syndrome type 4Corneal thinningCorneal thicknessCornea guttataType 4Observational cohort studyTertiary care settingComprehensive ophthalmic examinationSlit-lamp biomicroscopyCentral corneal thicknessCohort studyVisual acuityOphthalmic examinationPhenotype-genotype correlationClinical evaluationRefractive errorClinical assessmentCare settingsSpecular microscopyAnimal modelsYounger ageAxial lengthPathogenic mutationsTGFB2Human genome-wide association studies