State-Dependent Bidirectional Modification of Somatic Inhibition in Neocortical Pyramidal Cells
Kurotani T, Yamada K, Yoshimura Y, Crair MC, Komatsu Y. State-Dependent Bidirectional Modification of Somatic Inhibition in Neocortical Pyramidal Cells. Neuron 2008, 57: 905-916. PMID: 18367091, PMCID: PMC2880402, DOI: 10.1016/j.neuron.2008.01.030.Peer-Reviewed Original ResearchMeSH Keywords2-Amino-5-phosphonovalerateAction PotentialsAnimalsAnimals, NewbornBicucullineDendritesDose-Response Relationship, DrugDose-Response Relationship, RadiationElectric StimulationExcitatory Amino Acid AntagonistsGABA AntagonistsGamma-Aminobutyric AcidInhibitory Postsynaptic PotentialsNeural InhibitionPatch-Clamp TechniquesPyramidal CellsQuinoxalinesRatsRats, Sprague-DawleySpider VenomsVisual CortexConceptsL-type Ca2Slow-wave sleepSomatic inhibitionPyramidal neuronsLayer 5 pyramidal neuronsBidirectional modificationSlow membrane oscillationsRat visual cortexCortical pyramidal neuronsR-type Ca2Neocortical pyramidal cellsBehavioral statesNeuron responsivenessPyramidal cellsDepolarized phaseRepetitive firingVisual cortexReceptor exocytosisChannel activationInhibitionPotentiationNeuronsSleepMembrane oscillationsDepressionRetinocollicular Synapse Maturation and Plasticity Are Regulated by Correlated Retinal Waves
Shah RD, Crair MC. Retinocollicular Synapse Maturation and Plasticity Are Regulated by Correlated Retinal Waves. Journal Of Neuroscience 2008, 28: 292-303. PMID: 18171946, PMCID: PMC6671137, DOI: 10.1523/jneurosci.4276-07.2008.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAlpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic AcidAnimalsAnimals, NewbornBehavior, AnimalDose-Response Relationship, RadiationElectric StimulationExcitatory Amino Acid AntagonistsIn Vitro TechniquesMiceMice, KnockoutNeuronal PlasticityN-MethylaspartatePatch-Clamp TechniquesQuinoxalinesReceptors, NicotinicRetinaSuperior ColliculiSynapsesSynaptic TransmissionVisual PathwaysConceptsFirst postnatal weekRetinal wavesPostnatal weekSynapse maturationAMPA/NMDA ratioRetinotopic map refinementSpontaneous retinal wavesNicotinic ACh receptorsSecond postnatal weekRetinocollicular synapsesSynapses decreasesPattern of activationNMDA ratioSynaptic strengtheningACh receptorsQuantal amplitudeRetinotopic map formationSuperior colliculusControl synapsesSynaptic changesCoincident activityPlasticity protocolsFirst weekBeta2 subunitWeeks