2008
Mechanisms of response homeostasis during retinocollicular map formation
Shah RD, Crair MC. Mechanisms of response homeostasis during retinocollicular map formation. The Journal Of Physiology 2008, 586: 4363-4369. PMID: 18617562, PMCID: PMC2614012, DOI: 10.1113/jphysiol.2008.157222.Peer-Reviewed Original ResearchConceptsResponse homeostasisSynaptic plasticityIntrinsic excitabilityRetinocollicular map formationActivity-dependent developmentMouse superior colliculusHomeostatic plasticity mechanismsTotal synaptic inputReceptive fieldsDifferent mutant miceVisual receptive fieldsStrength of synapsesDifferent cellular mechanismsHebbian synaptic plasticityNeuronal outputSynaptic inputsSuperior colliculusRunaway excitationSynaptic scalingMutant miceNeural circuitsFunctional connectivityIndividual neuronsHomeostatic mechanismsCellular mechanisms
2007
Developmental Homeostasis of Mouse Retinocollicular Synapses
Chandrasekaran AR, Shah RD, Crair MC. Developmental Homeostasis of Mouse Retinocollicular Synapses. Journal Of Neuroscience 2007, 27: 1746-1755. PMID: 17301182, PMCID: PMC6673732, DOI: 10.1523/jneurosci.4383-06.2007.Peer-Reviewed Original ResearchMeSH KeywordsAlpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic AcidAnimalsAnimals, NewbornBrain MappingExcitatory Amino Acid AgonistsHomeostasisMembrane PotentialsMiceMice, Inbred C57BLMice, KnockoutModels, BiologicalNeuronsN-MethylaspartateReceptors, NicotinicRetinaSuperior ColliculiSynapsesVisual CortexVisual PathwaysConceptsRetinal wavesBeta2-/- miceSpontaneous retinal wavesRetinal ganglion cellsWild-type miceActivity-dependent competitionFirst postnatal weekTotal integrated responseLarge retinal areasTotal synaptic inputNeuronal receptive fieldsReceptive fieldsGanglion cellsPerturbation of activitiesSynaptic transmissionPostnatal weekResponse homeostasisSynaptic inputsRetinal areaRetinal inputSuperior colliculusStrong synapsesVisual cortexMutant miceRetinotopic mapping