2014
Sleep in Patients with Restrictive Lung Disease
Won CH, Kryger M. Sleep in Patients with Restrictive Lung Disease. Clinics In Chest Medicine 2014, 35: 505-512. PMID: 25156766, DOI: 10.1016/j.ccm.2014.06.006.ChaptersConceptsRestrictive lung diseaseLung diseaseObesity hypoventilation syndromeInterstitial lung diseasePathophysiology of sleepImpact of treatmentOverall prognosisVentilatory defectHypoventilation syndromeImpaired ventilationDaytime fatigueSleep disruptionRelated symptomsSleep disordersSleep qualityDiffusion impairmentNeuromuscular diseaseDiseasePatientsPathophysiologySleepHypoxemiaHypercarbiaPrognosisDysfunction
2010
Medication Effects on Sleep
Roux FJ, Kryger MH. Medication Effects on Sleep. Clinics In Chest Medicine 2010, 31: 397-405. PMID: 20488296, DOI: 10.1016/j.ccm.2010.02.008.Chapters
2007
Sleep apnea: Clinical investigations in humans
Banno K, Kryger MH. Sleep apnea: Clinical investigations in humans. Sleep Medicine 2007, 8: 400-426. PMID: 17478121, DOI: 10.1016/j.sleep.2007.03.003.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsObstructive sleep apnea syndromeCentral sleep apnea syndromeContinuous positive airway pressureSleep apnea syndromeApnea syndromeApneic episodesTreatment of OSASDiagnosis of SASUpper airway obstructionPositive airway pressureMuscles of respirationCessation of breathingCentral nervous systemAirway obstructionAirway pressureHeart failureOral appliancesRespiratory driveImpaired qualityAbnormal breathingSubjective symptomsDaytime sleepinessCommon disorderMetabolic dysfunctionSleep disruption
2000
Diagnosis and management of sleep apnea syndrome
Kryger M. Diagnosis and management of sleep apnea syndrome. Clinical Cornerstone 2000, 2: 39-44. PMID: 10875045, DOI: 10.1016/s1098-3597(00)90039-5.Peer-Reviewed Original ResearchConceptsSleep apnea syndromeApnea syndromeContinuous positive airway pressureMain presenting symptomPositive airway pressureSleep breathing disordersConstellation of signsPresenting symptomAirway pressureMost patientsExcessive daytimeSleep apneaBreathing disordersAbnormal breathingComplete resolutionSleep disruptionBusy cliniciansSymptomsSyndromeSleepDiagnosisDisordersEpisodesHypoxemiaApnea
1998
Effect of Pergolide on Restless Legs and Leg Movements in Sleep in Uremic Patients
Pieta J, Miliar T, Zacharias J, Fine A, Kryger M. Effect of Pergolide on Restless Legs and Leg Movements in Sleep in Uremic Patients. Sleep 1998, 21: 617-622. PMID: 9779521, DOI: 10.1093/sleep/21.6.617.Peer-Reviewed Original ResearchConceptsRestless legs syndromeLeg movementsRestless legsUremic patientsSubjective improvementTreatment of RLSDouble-blind placebo-controlled crossover studyPlacebo-controlled crossover studyRestless legs symptomsEffects of pergolideContinuous peritoneal dialysisPeriodic limb movementsSmall patient groupsHours of sleepQuality of sleepFirst hourChronic hemodialysisLeg symptomsCrossover studyLegs syndromePeritoneal dialysisIncremental dosesPatient groupSleep architectureSleep disruption
1996
L-DOPA/Carbidopa for Nocturnal Movement Disorders in Uremia
Walker S, Fine A, Kryger M. L-DOPA/Carbidopa for Nocturnal Movement Disorders in Uremia. Sleep 1996, 19: 214-218. PMID: 8723378, DOI: 10.1093/sleep/19.3.214.Peer-Reviewed Original ResearchConceptsL-dopa/carbidopaRestless legs syndromeSlow-wave sleepLeg movementsSleep timeTreatment of RLSMovement arousal indexNocturnal movement disordersSingle bedtime doseChronic hemodialysis patientsPeriodic limb movementsHours of sleepBedtime doseActive medicationHemodialysis patientsCrossover studyLegs syndromeUremic patientsArousal indexMovement disordersSleep disruptionFrequent dosingObjective improvementSleep disordersEffective treatmentEffect of severe gastroesophageal reflux on sleep stage in patients with aperistaltic esophagus
Shoenut J, Yamashiro Y, Orr W, Kerr P, Micflikier A, Kryger M. Effect of severe gastroesophageal reflux on sleep stage in patients with aperistaltic esophagus. Digestive Diseases And Sciences 1996, 41: 372-376. PMID: 8601385, DOI: 10.1007/bf02093831.Peer-Reviewed Original Research
1994
Effect of Inhaled 3% CO2 on Cheyne-Stokes Respiration in Congestive Heart Failure
Steens R, Millar T, Xiaoling S, Biberdorf D, Buckle P, Ahmed M, Kryger M. Effect of Inhaled 3% CO2 on Cheyne-Stokes Respiration in Congestive Heart Failure. Sleep 1994, 17: 61-68. PMID: 8191204, DOI: 10.1093/sleep/17.1.61.Peer-Reviewed Original ResearchConceptsStable congestive heart failureCheyne-Stokes respirationCongestive heart failureInhalation of CO2Heart failureSleep timeNocturnal arterial oxygen desaturationNight polysomnographic studiesArterial oxygen desaturationMovement sleep timeTotal sleep timeApnea indexOxygen desaturationMost patientsPolysomnographic studySleep latencySleep disruptionClinical significanceCardiac diseaseSleep structurePatientsNeurological diseasesNight 3Virtual abolitionShort duration
1982
Sleep, Arousals, and Oxygen Desaturation in Chronic Obstructive Pulmonary Disease
Fleetham J, West P, Mezon B, Conway W, Roth T, Kryger M. Sleep, Arousals, and Oxygen Desaturation in Chronic Obstructive Pulmonary Disease. American Journal Of Respiratory And Critical Care Medicine 1982, 126: 429-33. PMID: 7125332, DOI: 10.1164/arrd.1982.126.3.429.Peer-Reviewed Original ResearchConceptsOxygen desaturationArousal frequencySleep qualityChronic obstructive pulmonary diseaseAge-matched normal subjectsLower mean SaO2Role of hypoxemiaArterial oxygen desaturationObstructive pulmonary diseaseRoom air breathingArterial O2 saturationPoor sleep qualityReduced sleep timeSleep stage changesApneic episodesPulmonary functionOxygen therapyPulmonary diseaseSupplemental oxygenMean SaO2Sleep disruptionREM sleepNormal subjectsO2 saturationPatients