A transcriptomic axis predicts state modulation of cortical interneurons
Bugeon S, Duffield J, Dipoppa M, Ritoux A, Prankerd I, Nicoloutsopoulos D, Orme D, Shinn M, Peng H, Forrest H, Viduolyte A, Reddy C, Isogai Y, Carandini M, Harris K. A transcriptomic axis predicts state modulation of cortical interneurons. Nature 2022, 607: 330-338. PMID: 35794483, PMCID: PMC9279161, DOI: 10.1038/s41586-022-04915-7.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsArousalAxonsCalciumInterneuronsMiceNeural InhibitionReceptors, CholinergicTranscriptomeVisual CortexConceptsOscillatory brain statesInhibitory subtypesBrain statesPrimary visual cortexInhibitory neuronsIn vivo two-photon calcium imagingTwo-photon calcium imagingInhibitory cholinergic receptorsCortical inhibitory neuronsEx vivo slicesV1 subtypeVisual cortexCortical interneuronsDiverse patterns of activityLow input resistanceCholinergic receptorsState modulationInput resistanceCalcium imagingSubtypesAxonal projectionsCortical processingStateBrainNeurons