2014
Time for a Neonatal-Specific Consensus Definition for Sepsis
Wynn JL, Wong HR, Shanley TP, Bizzarro MJ, Saiman L, Polin RA. Time for a Neonatal-Specific Consensus Definition for Sepsis. Pediatric Critical Care Medicine 2014, 15: 523-528. PMID: 24751791, PMCID: PMC4087075, DOI: 10.1097/pcc.0000000000000157.Peer-Reviewed Original ResearchConceptsConsensus definitionNeonatal sepsisPreterm neonatesTerm neonatesPediatric consensus definitionsHost immune responseSepsis criteriaDevastating conditionLaboratory criteriaDiagnostic challengePediatric literatureClinical trialsObservational studyImmune responseSepsisNeonatesNew drugsDisease epidemiologyChildrenFuture trainingIntensivistsVariable definitionsEpidemiologyDiseaseTrialsLow‐Dose Intravenous Soybean Oil Emulsion for Prevention of Cholestasis in Preterm Neonates
Levit OL, Calkins KL, Gibson LC, Kelley‐Quon L, Robinson DT, Elashoff DA, Grogan TR, Li N, Bizzarro MJ, Ehrenkranz RA. Low‐Dose Intravenous Soybean Oil Emulsion for Prevention of Cholestasis in Preterm Neonates. Journal Of Parenteral And Enteral Nutrition 2014, 40: 374-382. PMID: 24963025, PMCID: PMC4537394, DOI: 10.1177/0148607114540005.Peer-Reviewed Original ResearchConceptsDays of lifeIntravenous fat emulsionPreterm neonatesPrimary outcomeGestational ageControl groupControl doseFat emulsionDays of PNFull enteral feedsPrevention of cholestasisMajor neonatal morbidityHours of lifeEffective preventive strategiesLow groupHospital stayNeonatal morbidityBaseline characteristicsParenteral nutritionSecondary outcomesEnteral feedsEssential fatty acidsPremature infantsLiver diseaseTotal bilirubin
2013
Temporal quantification of oxygen saturation ranges: an effort to reduce hyperoxia in the neonatal intensive care unit
Bizzarro MJ, Li FY, Katz K, Shabanova V, Ehrenkranz RA, Bhandari V. Temporal quantification of oxygen saturation ranges: an effort to reduce hyperoxia in the neonatal intensive care unit. Journal Of Perinatology 2013, 34: 33-38. PMID: 24071904, DOI: 10.1038/jp.2013.122.Peer-Reviewed Original ResearchConceptsSevere ROPRetinopathy of prematurityNeonatal intensive care unitIntensive care unitCare unitMultivariate analysisBronchopulmonary dysplasia/deathTarget saturation rangePost-intervention evaluationPreterm neonatesOxygen saturationStaff educationSurgeryInfantsMultidisciplinary groupSignificant reductionHyperoxiaDeathExposureSignal extraction technologyMorbidityPrematurityRetinopathyNeonates
2011
Risk factors for necrotizing enterocolitis totalis: a case–control study
Thompson A, Bizzarro M, Yu S, Diefenbach K, Simpson B, Moss R. Risk factors for necrotizing enterocolitis totalis: a case–control study. Journal Of Perinatology 2011, 31: 730-738. PMID: 21436786, DOI: 10.1038/jp.2011.18.Peer-Reviewed Original ResearchConceptsCase-control studyGestational ageEnterocolitis totalisBreast milkOdds ratioNewborn Special Care UnitYale-New Haven Children's HospitalRetrospective case-control studyFull enteral feedsGroup II controlsOccurrence of NECRisk of NECDate of diagnosisDays of diagnosisConfidence intervalsSpecial care unitsDays of lifePreterm patientsStudy patientsDate of birthPreterm neonatesCare unitChildren's HospitalGastrointestinal malformationsClinical events