2020
Analysis of Opioid-Seeking Behavior Through the Intravenous Self-Administration Reinstatement Model in Rats
Fattore L, Fadda P, Zanda M, Fratta W. Analysis of Opioid-Seeking Behavior Through the Intravenous Self-Administration Reinstatement Model in Rats. Methods In Molecular Biology 2020, 2201: 231-245. PMID: 32975804, DOI: 10.1007/978-1-0716-0884-5_21.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, IntravenousAnalgesics, OpioidAnimalsBehavior ControlBehavior, AddictiveConditioning, OperantCuesDisease Models, AnimalDrug-Seeking BehaviorHeroinInfusions, IntravenousMaleOpioid-Related DisordersRatsRats, Sprague-DawleyRats, WistarReinforcement, PsychologyRewardSelf AdministrationSubstance-Related DisordersConceptsNeurobiological mechanismsAnimal model of relapseExtinction-reinstatement modelHeroin-seeking behaviorReinstatement animal modelRelapse-like behaviorModel of relapseRelapse to heroinVulnerability to relapseNose poke responsesPanel press responseNonhuman primatesReinstatement modelDrug seekingLever pressOperant respondingDrug abstinenceAddiction researchVulnerability factorsPress responseSubstance useOperant responseAnimal modelsIndividual slipsSelf-administered
2018
Old and new synthetic cannabinoids: lessons from animal models
Zanda M, Fattore L. Old and new synthetic cannabinoids: lessons from animal models. Drug Metabolism Reviews 2018, 50: 54-64. PMID: 29376443, DOI: 10.1080/03602532.2018.1430824.Peer-Reviewed Original ResearchConceptsSynthetic cannabinoidsCannabinoid agonistsAnimal models of drug addictionConditioned place preference procedureModels of drug addictionPlace preference procedureBrain reward circuitsPositive reinforcing effectsDrug-induced behaviorsSynthetic cannabinoid agonistDelta-9-tetrahydrocannabinolReinstatement modelDrug discriminationReward circuitPreference procedureSelf-administrationAbuse liabilityPsychoactive componentAbuse potentialDrug addictionPsychiatric consequencesBehavioral studiesReinforcing effectsCannabinoidPsychoactive substances
2014
Analysis of Opioid-Seeking Reinstatement in the Rat
Fattore L, Fadda P, Zanda M, Fratta W. Analysis of Opioid-Seeking Reinstatement in the Rat. Methods In Molecular Biology 2014, 1230: 295-307. PMID: 25293336, DOI: 10.1007/978-1-4939-1708-2_25.Peer-Reviewed Original ResearchConceptsNeurobiological mechanismsAnimal model of relapseReinstatement animal modelRelapse-like behaviorHeroin-seeking behaviorRelapse to heroinVulnerability to relapseModel of relapseNose poke responsesPanel press responseNonhuman primatesReinstatement modelDrug seekingLever pressOperant respondingDrug abstinenceAddiction researchPress responseVulnerability factorsConditioned behaviorReinstatementSubstance useOperant responseAnimal modelsIndividual slips