A ~40-kb flavi-like virus does not encode a known error-correcting mechanism
Petrone M, Grove J, Mélade J, Mifsud J, Parry R, Marzinelli E, Holmes E. A ~40-kb flavi-like virus does not encode a known error-correcting mechanism. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2403805121. PMID: 39018195, PMCID: PMC11287256, DOI: 10.1073/pnas.2403805121.Peer-Reviewed Original ResearchConceptsFlavi-like virusGenome sizeRNA virusesRNA virus genomesNucleic acid metabolismGenome lengthPhylogenetic inferenceDeleterious mutationsExonuclease domainGenomeVirus genomeProofreading mechanismPopulation extinctionMutation rateRNAAcid metabolismExonucleaseMutationsVirusMetatranscriptomicsStructural analysisLineagesProofreadingMechanismMetabolism