2013
Does Kidney Disease Cause Hypertension?
Peixoto AJ, Orias M, Desir GV. Does Kidney Disease Cause Hypertension? Current Hypertension Reports 2013, 15: 89-94. PMID: 23344662, DOI: 10.1007/s11906-013-0327-6.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsChronic kidney diseaseKidney diseaseRenal functionStructural kidney diseaseGlomerular filtration ratePlasmin-mediated activationExtracellular fluid volumeProteinuric glomerular diseasesPolycystic kidney diseaseChronic hypertensionHypertension increasesEpithelial sodium channelSodium retentionFiltration rateGlomerular diseaseHypertensionCurrent evidenceDiseaseSodium channelsFluid volumeDetectable changeSevere reductionMost casesProteinuriaPatients
2009
Aliskiren and the Kidney: Beyond Hypertension
Trimarchi H, Orías M. Aliskiren and the Kidney: Beyond Hypertension. Nephrology Research & Reviews 2009, 1: 1-4. DOI: 10.4081/nr.2009.e1.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPlasma renin activityRenin activityReceptor blockersGlomerular diseaseRenin angiotensin aldosterone systemAldosterone receptor blockersEndstage kidney diseaseAngiotensin aldosterone systemAngiotensin receptor blockersRenal disease progressionSecondary glomerular diseasesUse of angiotensinRenin-angiotensin systemUrinary protein excretionNew therapeutic optionsDiabetic nephropathyProtein excretionKidney diseaseTherapeutic optionsDisease progressionComplete blockadeUrinary proteinSide effectsEnzyme inhibitorsImportant cause