2024
Strategies to Deimplement Opioid Prescribing in Primary Care
Quanbeck A, Robinson J, Jacobson N, Li X, Hennessy-Garza R, Landeck J, Cohen A, Madden L, Pulvermacher A, Brown R. Strategies to Deimplement Opioid Prescribing in Primary Care. JAMA Network Open 2024, 7: e2438325. PMID: 39388183, DOI: 10.1001/jamanetworkopen.2024.38325.Peer-Reviewed Original ResearchConceptsCluster randomized clinical trialDeimplementation strategiesMorphine milligram equivalent doseMorphine milligram equivalentsPractice facilitationOpioid prescribingIncreased screeningTreatment agreementsUS health care systemCenters for Disease Control and Prevention guidelinesRandomized clinical trialsUrine drug screensPrimary care clinicsPrimary care settingPrimary outcomeMental health screeningPain-related interferenceHealth care systemHigh-intensity groupEnjoyment of lifeChronic pain managementPrimary careCare clinicsCare settingsHealth screening
2022
What’s in a Name? Terminology Preferences Among Patients Receiving Methadone Treatment
Gazzola MG, Maclean E, Beitel M, Carmichael ID, Cammack KM, Eggert KF, Roehrich T, Madden LM, Jegede O, Zheng X, Bergman E, Barry DT. What’s in a Name? Terminology Preferences Among Patients Receiving Methadone Treatment. Journal Of General Internal Medicine 2022, 38: 653-660. PMID: 36163526, PMCID: PMC9971370, DOI: 10.1007/s11606-022-07813-w.Peer-Reviewed Original ResearchConceptsOpioid use disorderSubstance use disordersMethadone treatmentUse disordersOutpatient methadone treatment programMethadone treatment programsPresenting problemPreferences of patientsTerminology preferencesSubstance-dependent personsCross-sectional surveyAdult patientsMean ageUnivariate analysisMain MeasuresParticipantsPatientsTreatment programKey ResultsWeSubstance abuseSubstance useDisordersSignificant differencesTreatmentDemographic differencesAddiction counselorsCharacterizing the social support and functioning of a low-threshold medication for opioid use disorder treatment cohort at intake
Oles W, Alexander M, Kumar N, Howell B, O’Connor P, Madden LM, Barry DT. Characterizing the social support and functioning of a low-threshold medication for opioid use disorder treatment cohort at intake. BMC Psychiatry 2022, 22: 236. PMID: 35366844, PMCID: PMC8976510, DOI: 10.1186/s12888-022-03884-5.Peer-Reviewed Original ResearchConceptsLow-threshold clinicDemographic characteristicsOpioid use disorder treatmentMultivariate logistic regression modelBrief Pain InventoryPatient demographic characteristicsOpioid use disorderSocial supportSymptom Identification ScaleUse disorder treatmentNon-Hispanic whitesLogistic regression modelsOlder patientsPain InventoryTreatment cohortsSelf-reported social supportLife Events ChecklistMOUD treatmentBaseline disparitiesTreatment accessTreatment needsHigh riskUse disordersMortality rateDisorder treatment
2021
Successful transfer of stable patients on opioid agonist therapies from specialty addiction treatment to primary care settings in Ukraine: A pilot study
Meteliuk A, Galvez S, Fomenko T, Kalandiia H, Iaryi V, Farnum SO, Islam Z, Altice FL, Madden LM. Successful transfer of stable patients on opioid agonist therapies from specialty addiction treatment to primary care settings in Ukraine: A pilot study. Journal Of Substance Use And Addiction Treatment 2021, 134: 108619. PMID: 34579978, DOI: 10.1016/j.jsat.2021.108619.Peer-Reviewed Original ResearchConceptsOpioid agonist therapyPrimary care clinicsPrimary care settingOAT coverageAgonist therapyStable patientsCare clinicsSubstance useCare settingsNegative urine drug testsSpecialty addictions treatmentUrine drug testsSymptom Identification ScaleMental health symptomsAddiction treatment clinicsHIV transmissionPrimary careTreatment clinicsOAT patientsBASIS-24PatientsHealth symptomsEmotional labilityAddiction treatmentPilot studyA Pilot Investigation of Nonpharmacological Pain Management Intervention Groups in Methadone Maintenance Treatment
DiMeola KA, Haynes J, Barone M, Beitel M, Madden LM, Cutter CJ, Raso A, Gaeta M, Zheng X, Barry DT. A Pilot Investigation of Nonpharmacological Pain Management Intervention Groups in Methadone Maintenance Treatment. Journal Of Addiction Medicine 2021, 16: 229-234. PMID: 34145187, PMCID: PMC8678387, DOI: 10.1097/adm.0000000000000877.Peer-Reviewed Original ResearchConceptsMethadone maintenance treatmentCurrent pain intensityPain intensityMaintenance treatmentAcute increaseIntervention groupCurrent chronic painMood statesCognitive behavioral therapyMMT clinicsChronic painAcute improvementAcute reductionAcute changesSpecific mood statesPainExergame interventionGroup attendanceUnvalidated measuresMonday-FridayPilot investigationBonferroni correctionPatientsT-testIntervention“A good mother”: Impact of motherhood identity on women's substance use and engagement in treatment across the lifespan
Adams ZM, Ginapp CM, Price CR, Qin Y, Madden LM, Yonkers K, Meyer JP. “A good mother”: Impact of motherhood identity on women's substance use and engagement in treatment across the lifespan. Journal Of Substance Use And Addiction Treatment 2021, 130: 108474. PMID: 34118710, PMCID: PMC8478714, DOI: 10.1016/j.jsat.2021.108474.Peer-Reviewed Original ResearchConceptsSUD treatmentSubstance useSubstance use disorder treatmentSUD treatment programsUse disorder treatmentWomen's substance usePostpartum periodMost womenStudy staffIndependent authorsTreatment engagementDisorder treatmentTreatment programWomenSUD recoveryTreatmentMothersSpecific barriersChildrenResidential programsMiddle adulthoodFocus groupsCaretakersQualitative interviewsPregnancyPsychiatric comorbidity and order of condition onset among patients seeking treatment for chronic pain and opioid use disorder
Barry DT, Beitel M, Cutter CJ, Fiellin DA, Madden LM, Lipkind N, Bollampally P, Liong C, Schottenfeld RS. Psychiatric comorbidity and order of condition onset among patients seeking treatment for chronic pain and opioid use disorder. Drug And Alcohol Dependence 2021, 221: 108608. PMID: 33667784, PMCID: PMC8026725, DOI: 10.1016/j.drugalcdep.2021.108608.Peer-Reviewed Original ResearchConceptsOpioid use disorderChronic painPsychiatric comorbidityCondition onsetUse disordersNonopioid substance use disordersDSM-IV-TR Axis I DisordersFirst groupComorbid chronic painStructured Clinical InterviewAxis I DisordersAxis II disordersSubstance use disordersDSM-IV personality disordersStandardized training protocolSame time groupsPotential treatment implicationsClinical trialsDoctoral-level providersI disordersMultinomial logistic regressionPrimary drugClinical InterviewPainDiagnostic Interview
2020
A qualitative investigation of addiction counselors' perceptions and experiences implementing an open-access model for treating opioid use disorder
Oberleitner LMS, Madden LM, Muthulingam D, Marcus R, Oberleitner DE, Beitel M, Gaeta M, Tamberelli JF, Barry DT. A qualitative investigation of addiction counselors' perceptions and experiences implementing an open-access model for treating opioid use disorder. Journal Of Substance Use And Addiction Treatment 2020, 121: 108191. PMID: 33357602, PMCID: PMC7770334, DOI: 10.1016/j.jsat.2020.108191.Peer-Reviewed Original ResearchConceptsMethadone maintenance treatmentTreatment programOpioid treatment programsOpioid use disorderMaintenance treatmentTreatment optionsMethadone maintenanceUse disordersProspective patientsIndividual semi-structured interviewsCounselors' perceptionsTreatment organizationsInterdisciplinary teamCliniciansAddiction counselorsSemi-structured interviewsCorrelates of Homelessness Among Patients in Methadone Maintenance Treatment
Gaeta M, Beitel M, Oberleitner LMS, Oberleitner DE, Madden LM, Tamberelli JF, Barry DT. Correlates of Homelessness Among Patients in Methadone Maintenance Treatment. Medical Care 2020, 58: 1030-1034. PMID: 32925463, PMCID: PMC7668351, DOI: 10.1097/mlr.0000000000001414.Peer-Reviewed Original ResearchConceptsOpioid use disorderImportant public health roleLogistic regressionMethadone maintenance treatment programImportant public health issueTreatment-related correlatesCorrelates of homelessnessPercent of patientsMethadone maintenance treatmentFinal logistic regression modelMaintenance treatment programPublic health roleSymptoms of depressionBivariate logistic regressionPublic health issueLogistic regression modelsMaintenance treatmentUse disordersPatientsSignificant independent variablesHealth roleBivariate analysisTreatment programPast monthHigher symptomsThe real‐world impact of dosing of methadone and buprenorphine in retention on opioid agonist therapies in Ukraine
Farnum SO, Makarenko I, Madden L, Mazhnaya A, Marcus R, Prokhorova T, Bojko MJ, Rozanova J, Dvoriak S, Islam Z, Altice FL. The real‐world impact of dosing of methadone and buprenorphine in retention on opioid agonist therapies in Ukraine. Addiction 2020, 116: 83-93. PMID: 32428276, PMCID: PMC7674222, DOI: 10.1111/add.15115.Peer-Reviewed Original ResearchConceptsOpioid agonist therapyOAT discontinuationAgonist therapyTreatment retentionIndependent predictorsHIV epidemicCost-effective HIV prevention strategyMethadone maintenance treatment patientsObservational longitudinal cohort studySpecialty addictions treatmentBuprenorphine maintenance treatmentHigh dosageHIV prevention strategiesLongitudinal cohort studyOpioid-dependent peopleTreatment discontinuationCohort studyMaintenance treatmentMale sexTreatment patientsPrevention strategiesDiscontinuationYounger ageCenter settingAddiction treatmentCorrelates of sleep quality and excessive daytime sleepiness in people with opioid use disorder receiving methadone treatment
Baldassarri SR, Beitel M, Zinchuk A, Redeker NS, Oberleitner DE, Oberleitner LMS, Carrasco D, Madden LM, Lipkind N, Fiellin DA, Bastian LA, Chen K, Yaggi HK, Barry DT. Correlates of sleep quality and excessive daytime sleepiness in people with opioid use disorder receiving methadone treatment. Sleep And Breathing 2020, 24: 1729-1737. PMID: 32556918, PMCID: PMC7680294, DOI: 10.1007/s11325-020-02123-z.Peer-Reviewed Original ResearchConceptsOpioid use disorderExcessive daytime sleepinessDaytime sleepinessSleep qualityChronic painExcessive daytimeUse disordersConclusionsPoor sleep qualityCurrent chronic painModifiable risk factorsImpaired sleep qualityMultivariable linear regression modelsBody mass indexPoor sleep qualityNon-significant associationMass indexMultivariable analysisPain interferenceRelated comorbiditiesMethadone treatmentClinical correlatesMean PSQIRisk factorsSleep disordersResultsNinety percentWomen’s Decision-Making about PrEP for HIV Prevention in Drug Treatment Contexts
Qin Y, Price C, Rutledge R, Puglisi L, Madden LM, Meyer JP. Women’s Decision-Making about PrEP for HIV Prevention in Drug Treatment Contexts. Journal Of The International Association Of Providers Of AIDS Care (JIAPAC) 2020, 19: 2325958219900091. PMID: 31918605, PMCID: PMC7099671, DOI: 10.1177/2325958219900091.Peer-Reviewed Original ResearchConceptsSubstance use disordersDrug treatment centersHIV preventionTreatment centersPre-exposure prophylaxis efficacyOwn HIV riskDrug treatment contextIntervenable targetPrEP interventionsPrEP awarenessProphylaxis efficacyHIV riskEarly recoveryUse disordersPrEPWomenPreventionTreatment contextSemistructured interviewsEfficacyRiskWomen's abilityLong-term systemic changesWomen's lackDecision-making skills
2019
Pain catastrophizing and pain acceptance are associated with pain severity and interference among methadone‐maintained patients
Mun CJ, Beitel M, Oberleitner L, Oberleitner DE, Madden LM, Bollampally P, Barry DT. Pain catastrophizing and pain acceptance are associated with pain severity and interference among methadone‐maintained patients. Journal Of Clinical Psychology 2019, 75: 2233-2247. PMID: 31454081, PMCID: PMC7213971, DOI: 10.1002/jclp.22842.Peer-Reviewed Original ResearchConceptsOpioid use disorderMethadone maintenance treatmentPain severityPain acceptanceChronic painPain interferenceMMT patientsUse disordersCo-occurring opioid use disorderMethadone-maintained patientsMethadone doseImportant intervention targetMaintenance treatmentPain catastrophizingPainPsychosocial interventionsPatientsIntervention targetsPrevious weekSeverityEmotional distressImportant targetSelf-report measuresDisordersPresent studyPhysicians’ satisfaction with providing buprenorphine treatment
Knudsen HK, Brown R, Jacobson N, Horst J, Kim JS, Collier E, Starr S, Madden LM, Haram E, Toy A, Molfenter T. Physicians’ satisfaction with providing buprenorphine treatment. Addiction Science & Clinical Practice 2019, 14: 34. PMID: 31446893, PMCID: PMC6709557, DOI: 10.1186/s13722-019-0163-3.Peer-Reviewed Original ResearchConceptsBuprenorphine treatmentBaseline Web-based surveyOpioid use disorderGeneral medical practiceStudy of physiciansMedical practiceWaivered physiciansTreatment recommendationsClinical trialsRisk factorsOpioid epidemicImportant treatmentMethodsAs partUse disordersWeb-based surveyPhysician job satisfactionPhysiciansTreatment organizationsBuprenorphineSignificant differencesTreatmentOverall satisfactionSatisfaction itemsStudy measuresLower satisfactionUsing nominal group technique to identify barriers, facilitators, and preferences among patients seeking treatment for opioid use disorder: A needs assessment for decision making support
Muthulingam D, Bia J, Madden LM, Farnum SO, Barry DT, Altice FL. Using nominal group technique to identify barriers, facilitators, and preferences among patients seeking treatment for opioid use disorder: A needs assessment for decision making support. Journal Of Substance Use And Addiction Treatment 2019, 100: 18-28. PMID: 30898324, PMCID: PMC6432946, DOI: 10.1016/j.jsat.2019.01.019.Peer-Reviewed Original ResearchConceptsOpioid use disorderNominal group techniquePharmacologic therapyUse disordersSyringe exchange programsIndividual-level barriersEvidence-based interventionsAddiction treatment centersEvidence-based strategiesOUD treatmentPharmacologic treatmentSpecific medicationsTreatment optionsPharmacologic propertiesMedicationsDecision aidPatient considerationsSide effectsTreatment centersOpioid crisisSpecific knowledge gapsGroup techniqueDecision aid developmentTreatmentTherapyElectronic cigarette and tobacco use in individuals entering methadone or buprenorphine treatment
Baldassarri SR, Fiellin DA, Savage ME, Madden LM, Beitel M, Dhingra LK, Fucito L, Camenga D, Bollampally P, Barry DT. Electronic cigarette and tobacco use in individuals entering methadone or buprenorphine treatment. Drug And Alcohol Dependence 2019, 197: 37-41. PMID: 30769264, PMCID: PMC6637405, DOI: 10.1016/j.drugalcdep.2018.12.012.Peer-Reviewed Original ResearchConceptsOpioid use disorderOpioid agonist therapyCurrent cigarette smokingCigarette smokingEC useHigher oddsFormer smokersLower oddsPsychiatric distressPast cigarette smokingElectronic cigarette useAgonist therapyCurrent smokersBuprenorphine treatmentChronic painTobacco useNicotine dependenceUse disordersSmokingCigarette useMultivariate analysisElectronic cigarettesSmokersCigarettesMultivariate model
2018
An evaluation of the feasibility, acceptability, and preliminary efficacy of cognitive-behavioral therapy for opioid use disorder and chronic pain
Barry DT, Beitel M, Cutter CJ, Fiellin DA, Kerns RD, Moore BA, Oberleitner L, Madden LM, Liong C, Ginn J, Schottenfeld RS. An evaluation of the feasibility, acceptability, and preliminary efficacy of cognitive-behavioral therapy for opioid use disorder and chronic pain. Drug And Alcohol Dependence 2018, 194: 460-467. PMID: 30508769, PMCID: PMC6312460, DOI: 10.1016/j.drugalcdep.2018.10.015.Peer-Reviewed Original ResearchConceptsOpioid use disorderCognitive behavioral therapyChronic painPreliminary efficacyDrug counselingUse disordersImproved pain outcomesProportion of patientsMethadone-maintained patientsNonmedical opioid useEnd of treatmentPrimary study aimPatient satisfaction ratingsManualized cognitive behavioral therapyOpioid usePain outcomesPain interferenceClinical trialsStandard drug counselingPatientsMean sessionSecondary aimStudy aimPainPilot studyAssessment of barrier severity and willingness to enter opioid agonist treatment among people who inject drugs in Ukraine
Zelenev A, Shea P, Mazhnaya A, Rozanova J, Madden L, Marcus R, Altice FL. Assessment of barrier severity and willingness to enter opioid agonist treatment among people who inject drugs in Ukraine. Drug And Alcohol Dependence 2018, 190: 82-88. PMID: 29990648, PMCID: PMC6292439, DOI: 10.1016/j.drugalcdep.2018.05.027.Peer-Reviewed Original ResearchConceptsOpioid agonist therapyOpioid agonist treatmentOpioid-dependent peopleSubstance abuse treatment programsCross-sectional surveyAgonist therapyAgonist treatmentHIV preventionTreatment perceptionsTreatment efficacyOAT expansionStudy participantsTreatment programAddiction treatmentComposite measureSeveritySocial stigmaDrugsTreatmentStructural barriersBarrier severityParticipantsExperiences of Burnout among Drug Counselors in A Large Opioid Treatment Program: A Qualitative Investigation
Beitel M, Oberleitner L, Muthulingam D, Oberleitner D, Madden LM, Marcus R, Eller A, Bono MH, Barry DT. Experiences of Burnout among Drug Counselors in A Large Opioid Treatment Program: A Qualitative Investigation. Substance Use & Addiction Journal 2018, 39: 211-217. PMID: 29522381, DOI: 10.1080/08897077.2018.1449051.Peer-Reviewed Original ResearchConceptsExperience of burnoutDrug counselorsTreatment programJob-related demandsIndividual semi-structured interviewsWork engagementCounselor burnoutBurnoutCounselor feedbackPhysiological symptomsSemi-structured interviewsCounselorsQualitative investigationParticipantsPossible experienceSystem-level changesCounselor descriptionsExperienceProgram settingsOpioid treatment programsTreatment gapMultidisciplinary teamEngagementProgramTranscribedAn investigation of an open‐access model for scaling up methadone maintenance treatment
Madden LM, Farnum SO, Eggert KF, Quanbeck AR, Freeman RM, Ball SA, Schottenfeld RS, Shi JM, Savage ME, Barry DT. An investigation of an open‐access model for scaling up methadone maintenance treatment. Addiction 2018, 113: 1450-1458. PMID: 29453891, DOI: 10.1111/add.14198.Peer-Reviewed Original ResearchConceptsNon-medical opioid useOpioid use disorderMethadone maintenance treatmentOpioid useMaintenance treatmentTreatment accessUse disordersTreatment modelMethadone maintenance treatment centersMaintenance treatment centersDeleterious effectsMethadone treatmentPatient mortalityTreatment optionsTreatment outcomesTreatment centersProspective patientsRate of retentionPatient censusRapid enrollmentAddiction treatmentApparent deleterious effectsTreatmentMortalityProgrammatic outcomes