2024
Melanocortin-1 Receptor Expression as a Marker of Progression in Melanoma
Su D, Djureinovic D, Schoenfeld D, Marquez-Nostra B, Olino K, Jilaveanu L, Kluger H. Melanocortin-1 Receptor Expression as a Marker of Progression in Melanoma. JCO Precision Oncology 2024, 8: e2300702. PMID: 38662983, PMCID: PMC11513442, DOI: 10.1200/po.23.00702.Peer-Reviewed Original ResearchConceptsMC1R expressionMelanoma progressionAssociated with shorter survivalStages of melanoma progressionCases of benign neviChronic sun exposureMarkers of progressionHuman melanoma tissuesBreslow thicknessMelanocortin-1Metastatic melanomaOverall survivalPrimary melanomaMetastatic tumorsMelanoma cohortReceptor expressionPredictive biomarkersAggressive melanomaPrimary lesionTissue microarrayShorter survivalMale sexQuantitative immunofluorescenceBenign neviClinical trials
2016
CEACAM1: Expression and Role in Melanocyte Transformation
Turcu G, Nedelcu RI, Ion DA, Brînzea A, Cioplea MD, Jilaveanu LB, Zurac SA. CEACAM1: Expression and Role in Melanocyte Transformation. Disease Markers 2016, 2016: 9406319. PMID: 27642217, PMCID: PMC5013198, DOI: 10.1155/2016/9406319.Peer-Reviewed Original ResearchConceptsCarcinoembryonic antigen cell adhesion molecule 1Melanoma patientsCell adhesion molecule-1Standard immunohistochemical panelImmune checkpoint inhibitorsSubgroup of patientsAdhesion molecule-1Development of melanomaAggressive therapyCheckpoint inhibitorsAdvanced melanomaPoor prognosisMetastatic melanomaImmunohistochemical panelCell adhesion moleculeMelanoma treatmentMolecule-1New biomarkersPatientsMelanoma progressionAdhesion moleculesMelanoma cellsMelanomaNormal melanocytesTherapy