Evolving Strategies for the Management of Obstructive Hypertrophic Cardiomyopathy
Liang L, Lumish H, Sewanan L, Shimada Y, Maurer M, Weiner S, Clerkin K. Evolving Strategies for the Management of Obstructive Hypertrophic Cardiomyopathy. Journal Of Cardiac Failure 2024, 30: 1136-1153. PMID: 38777216, PMCID: PMC11415289, DOI: 10.1016/j.cardfail.2024.04.024.Peer-Reviewed Original ResearchObstructive hypertrophic cardiomyopathyHypertrophic cardiomyopathyObstructive HCMLeft ventricular outflow tract obstructionVentricular outflow tract obstructionImproved cardiac energeticsSeptal reduction therapyOutflow tract obstructionTreatment of hypertrophic cardiomyopathyRandomized clinical trialsReal-world populationSpecific therapiesPatient selectionHeterogeneous diseaseReduction therapyClinical trialsCardiac energeticsMavacamtenExercise capacityActin-myosin interactionPatientsMyosin modulatorsCardiomyopathyLong-term dataTherapy