2020
ABC score: a new risk score that accurately predicts mortality in acute upper and lower gastrointestinal bleeding: an international multicentre study
Laursen SB, Oakland K, Laine L, Bieber V, Marmo R, Redondo-Cerezo E, Dalton HR, Ngu J, Schultz M, Soncini M, Gralnek I, Jairath V, Murray IA, Stanley AJ. ABC score: a new risk score that accurately predicts mortality in acute upper and lower gastrointestinal bleeding: an international multicentre study. Gut 2020, 70: 707-716. PMID: 32723845, DOI: 10.1136/gutjnl-2019-320002.Peer-Reviewed Original ResearchConceptsLower gastrointestinal bleedingABC scoreLower riskHigher ABC scoresGastrointestinal bleedingRisk scoreMortality rateHospital mortality rateInternational cohort studyManagement of patientsNew risk scoreInternational multicentre studyLower ABC scoreLGIB patientsUGIB patientsComorbidity scoreCohort studyMulticentre studyBlood testsValidation cohortDevelopment cohortLGIBUGIBHigh riskPatients
2001
Approaches to nonsteroidal anti-inflammatory drug use in the high-risk patient
Laine L. Approaches to nonsteroidal anti-inflammatory drug use in the high-risk patient. Gastroenterology 2001, 120: 594-606. PMID: 11179238, DOI: 10.1053/gast.2001.21907.Peer-Reviewed Original ResearchConceptsNonsteroidal anti-inflammatory drugsGI eventsGI diseasePrevention of NSAIDAnti-inflammatory drug useClinical upper GI eventsHistory of ulcerUpper GI eventsHalf of patientsHigh-risk patientsAnti-inflammatory drugsGastrointestinal eventsNSAID doseGastroduodenal injuryNSAID usersClinical featuresGastric erosionsSteroid useCommon causeDrug usePatientsUlcersDiseaseRiskUnited States today