2020
Use of Fecal Occult Blood Testing as a Diagnostic Tool for Clinical Indications: A Systematic Review and Meta-Analysis.
Lee MW, Pourmorady JS, Laine L. Use of Fecal Occult Blood Testing as a Diagnostic Tool for Clinical Indications: A Systematic Review and Meta-Analysis. The American Journal Of Gastroenterology 2020, 115: 662-670. PMID: 31972617, DOI: 10.14309/ajg.0000000000000495.Peer-Reviewed Original ResearchConceptsFecal occult blood testIron deficiency anemiaSensitivity of FOBTAcute diarrheaClinical indicationsSystematic reviewFecal occult blood testingDiagnostic testsSpecific gastrointestinal symptomsOccult blood testingPrimary end pointOccult blood testColorectal cancer screeningPositive stool cultureRisk of biasQUADAS-2 toolGastrointestinal symptomsAdult patientsEndoscopic evaluationUlcerative colitisEndoscopic activityBlood testsIdentifiable causeStool culturesBlood testing
2017
Randomized trial of cholangioscopy-guided laser lithotripsy versus conventional therapy for large bile duct stones (with videos)
Buxbaum J, Sahakian A, Ko C, Jayaram P, Lane C, Yu CY, Kankotia R, Laine L. Randomized trial of cholangioscopy-guided laser lithotripsy versus conventional therapy for large bile duct stones (with videos). Gastrointestinal Endoscopy 2017, 87: 1050-1060. PMID: 28866457, DOI: 10.1016/j.gie.2017.08.021.Peer-Reviewed Original ResearchConceptsCholangioscopy-guided laser lithotripsyBile duct stonesDuct stonesConventional therapyLaser lithotripsy groupEndoscopic clearanceMechanical lithotripsyBalloon dilationLaser lithotripsyLithotripsy groupProcedure timeLarge common bile duct stonesCommon bile duct stonesLarge bile duct stonesConventional therapy groupHistory of ERCPCommon duct explorationPost-ERCP pancreatitisLarge bile ductsCholangioscopy-guided lithotripsyLonger procedure timeSuccessful endoscopic extractionNumber of proceduresAdverse eventsDuct exploration
2014
Quality indicators for EGD
Park WG, Shaheen NJ, Cohen J, Pike IM, Adler DG, Inadomi JM, Laine LA, Lieb JG, Rizk MK, Sawhney MS, Wani S. Quality indicators for EGD. Gastrointestinal Endoscopy 2014, 81: 17-30. PMID: 25480101, DOI: 10.1016/j.gie.2014.07.057.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsQuality Indicators for EGD
Park WG, Shaheen NJ, Cohen J, Pike IM, Adler DG, Inadomi JM, Laine LA, Lieb JG, Rizk MK, Sawhney MS, Wani S. Quality Indicators for EGD. The American Journal Of Gastroenterology 2014, 110: 60. PMID: 25448872, DOI: 10.1038/ajg.2014.384.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2013
The Utility of Esophagogastroduodenoscopy Before Endoscopic Ultrasonography in Patients Undergoing Endoscopic Ultrasonography for Pancreatico-biliary and Mediastinal Indications
Sahakian AB, Aslanian HR, Mehra M, Rossi F, Laine L, Sanchez M, Ciarleglio MM, Adimoolam V, Siddiqui UD. The Utility of Esophagogastroduodenoscopy Before Endoscopic Ultrasonography in Patients Undergoing Endoscopic Ultrasonography for Pancreatico-biliary and Mediastinal Indications. Journal Of Clinical Gastroenterology 2013, 47: 857-860. PMID: 23632349, DOI: 10.1097/mcg.0b013e31828ba28c.Peer-Reviewed Original ResearchConceptsEndoscopic ultrasonographyMeaningful lesionsMedical managementEUS examinationMulticenter prospective cohort studyLarge community practiceUtility of esophagogastroduodenoscopyProportion of patientsProspective cohort studyTertiary referral centerLarge hiatal herniaCohort studyReferral centerHiatal herniaPrimary outcomeBarrett's esophagusProspective dataLuminal lesionsPractice patternsEsophagogastroduodenoscopyNeoplastic lesionsOblique-viewing echoendoscopesHyperplastic gastricPatientsCombined outcome
2008
Endoscopic Therapy for Bleeding Ulcers: An Evidence-Based Approach Based on Meta-Analyses of Randomized Controlled Trials
Laine L, McQuaid KR. Endoscopic Therapy for Bleeding Ulcers: An Evidence-Based Approach Based on Meta-Analyses of Randomized Controlled Trials. Clinical Gastroenterology And Hepatology 2008, 7: 33-47. PMID: 18986845, DOI: 10.1016/j.cgh.2008.08.016.Peer-Reviewed Original ResearchMeSH KeywordsCoagulantsElectrocoagulationEndoscopy, Digestive SystemEpinephrineHemorrhageHot TemperatureHumansProton Pump InhibitorsSclerosing SolutionsSurgical InstrumentsTreatment OutcomeUlcerConceptsEndoscopic therapyProton pump inhibitorsActive bleedingVisible vesselPump inhibitorsIntravenous proton pump inhibitorsAppropriate endoscopic treatmentNonbleeding visible vesselPrimary end pointSecond-look endoscopyEndoscopic hemostatic therapyRandomized Controlled TrialsEvidence-based approachPlacebo/Further bleedingHemostatic therapyInjection therapyControlled TrialsEndoscopic treatmentRandomized trialsBleeding ulcersSclerosant therapyReceptor antagonistBibliographic database searchBleedingA systematic review and meta-analysis of randomized, controlled trials of moderate sedation for routine endoscopic procedures
McQuaid KR, Laine L. A systematic review and meta-analysis of randomized, controlled trials of moderate sedation for routine endoscopic procedures. Gastrointestinal Endoscopy 2008, 67: 910-923. PMID: 18440381, DOI: 10.1016/j.gie.2007.12.046.Peer-Reviewed Original ResearchMeSH KeywordsConscious SedationDigestive System DiseasesEndoscopy, Digestive SystemHumansRandomized Controlled Trials as TopicConceptsModerate sedationPatient satisfactionAdverse eventsPhysician assessmentSystematic reviewSedation-related complicationsSerious adverse eventsPoor methodologic qualitySuperior patient satisfactionRoutine endoscopic proceduresComputerized bibliographic databasesActive regimenActive regimensLonger sedationRandomized trialsPatient assessmentMethodologic qualityAvailable agentsProcedure timeEndoscopic proceduresLower riskSedationMidazolamRegimensPropofol
1999
Helicobacter pylori: drowning in a pool of blood?
Laine L, Cohen H. Helicobacter pylori: drowning in a pool of blood? Gastrointestinal Endoscopy 1999, 49: 398-402. PMID: 10049431, DOI: 10.1016/s0016-5107(99)70024-6.Commentaries, Editorials and Letters
1998
Effect of blood on rapid urease testing of gastric mucosal biopsy specimens
Laine L, Sidhom O, Emami S, Estrada R, Cohen H. Effect of blood on rapid urease testing of gastric mucosal biopsy specimens. Gastrointestinal Endoscopy 1998, 47: 141-143. PMID: 9512278, DOI: 10.1016/s0016-5107(98)70346-3.Peer-Reviewed Original ResearchMeSH KeywordsBiopsyEndoscopy, Digestive SystemGastric MucosaHelicobacter InfectionsHelicobacter pyloriHumansUreaseConceptsRapid urease testBiopsy specimensUrease testEffect of bloodRapid urease test resultsGastric mucosal biopsy specimensMucosal biopsy specimensRapid urease testingGastric biopsy specimensUrease test resultsGastric bodyUrease testingPositive testDiscordant resultsBloodCLOtestPyloriTekHoursPatientsAntrumBiopsyMucosaEndoscopy
1997
Management of actively bleeding esophageal varices
Laine L. Management of actively bleeding esophageal varices. Gastrointestinal Endoscopy 1997, 46: 83-84. PMID: 9260714, DOI: 10.1016/s0016-5107(97)70218-9.Commentaries, Editorials and LettersProspective comparison of H&E, Giemsa, and Genta stains for the diagnosis of Helicobacter pylori
Laine L, Lewin D, Naritoku W, Cohen H. Prospective comparison of H&E, Giemsa, and Genta stains for the diagnosis of Helicobacter pylori. Gastrointestinal Endoscopy 1997, 45: 463-467. PMID: 9199901, DOI: 10.1016/s0016-5107(97)70174-3.Peer-Reviewed Original Research
1995
Interobserver agreement and predictive value of endoscopic findings for H. pylori and gastritis in normal volunteers
Laine L, Cohen H, Sloane R, Marin-Sorensen M, Weinstein W. Interobserver agreement and predictive value of endoscopic findings for H. pylori and gastritis in normal volunteers. Gastrointestinal Endoscopy 1995, 42: 420-423. PMID: 8566631, DOI: 10.1016/s0016-5107(95)70043-9.Peer-Reviewed Original ResearchConceptsAntral nodularityPositive predictive valueH. pyloriPredictive valueArea gastricaeEndoscopic findingsEndoscopic featuresInterobserver agreementDiagnostic valueH. pylori gastritisSpecific endoscopic featuresGastric bodyHistologic gastritisPylori gastritisBiopsy specimensHealthy subjectsGastritisNormal volunteersHelicobacter pyloriFull endoscopyPyloriNodularityReproducible findingsErythema
1993
Refining the prognostic value of endoscopy in patients presenting with bleeding ulcers
Laine L. Refining the prognostic value of endoscopy in patients presenting with bleeding ulcers. Gastrointestinal Endoscopy 1993, 39: 461-462. PMID: 8514088, DOI: 10.1016/s0016-5107(93)70132-7.Peer-Reviewed Original ResearchBlood CoagulationBlood VesselsEndoscopy, Digestive SystemHumansPeptic Ulcer HemorrhagePrognosisRecurrenceRisk Factors