2024
AGA Clinical Practice Update on High-Quality Upper Endoscopy: Expert Review
Nagula S, Parasa S, Laine L, Shah S. AGA Clinical Practice Update on High-Quality Upper Endoscopy: Expert Review. Clinical Gastroenterology And Hepatology 2024, 22: 933-943. PMID: 38385942, DOI: 10.1016/j.cgh.2023.10.034.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsClinical Practice UpdateAmerican Gastroenterological Association (AGA) Institute Clinical Practice UpdateUpper endoscopySurveillance intervalsPractice updateExpert reviewAGA Governing BoardConsensus-based expert opinionStandard biopsy protocolUpper endoscopic examinationPractice advice statementsPeer reviewUpper gastrointestinal mucosaInternational peer reviewAGA membershipBiopsy protocolSurveillance endoscopyDiagnostic yieldHistopathological resultsEndoscopic findingsRetroflexed viewCharacterization of abnormalitiesEndoscopic examinationEndoscopyAdequate visualization
2018
Image-enhanced endoscopy is specific for the diagnosis of non-erosive gastroesophageal reflux disease
Parikh ND, Viana AV, Shah S, Laine L. Image-enhanced endoscopy is specific for the diagnosis of non-erosive gastroesophageal reflux disease. Scandinavian Journal Of Gastroenterology 2018, 53: 260-264. PMID: 29368532, PMCID: PMC6080852, DOI: 10.1080/00365521.2018.1430847.Peer-Reviewed Original ResearchConceptsNon-erosive gastroesophageal reflux diseaseGastroesophageal reflux diseaseImage-enhanced endoscopyNarrow-band imagingReflux diseaseEndoscopic findingsSquamocolumnar junctionUpper endoscopyPatient acceptanceEndoscopyBand imagingI-scanVascularityAdditional studiesPit patternHeartburnPatientsDiseaseDiagnosisImpedance monitoringRRSpecificityFindingsControlCases
2017
Narrow-band imaging versus white light versus mapping biopsy for gastric intestinal metaplasia: a prospective blinded trial
Buxbaum JL, Hormozdi D, Dinis-Ribeiro M, Lane C, Dias-Silva D, Sahakian A, Jayaram P, Pimentel-Nunes P, Shue D, Pepper M, Cho D, Laine L. Narrow-band imaging versus white light versus mapping biopsy for gastric intestinal metaplasia: a prospective blinded trial. Gastrointestinal Endoscopy 2017, 86: 857-865. PMID: 28366441, DOI: 10.1016/j.gie.2017.03.1528.Peer-Reviewed Original ResearchConceptsGastric intestinal metaplasiaDetection of GIMNarrow-band imagingHD-WLMapping biopsyIntestinal metaplasiaHigh-definition white light endoscopyProportion of patientsProspective blinded trialGastric cancer precursorsGastric cancer riskWhite light endoscopyNBI examinationPrimary outcomeUpper endoscopyHigher proportionBlinded trialCancer precursorsBiopsy specimensMedian numberSecond endoscopistGastric cancerCancer riskBiopsyPatients
2014
Causes of Bleeding and Outcomes in Patients Hospitalized With Upper Gastrointestinal Bleeding
Kim JJ, Sheibani S, Park S, Buxbaum J, Laine L. Causes of Bleeding and Outcomes in Patients Hospitalized With Upper Gastrointestinal Bleeding. Journal Of Clinical Gastroenterology 2014, 48: 113-118. PMID: 23685847, DOI: 10.1097/mcg.0b013e318297fb40.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overEndoscopy, GastrointestinalEsophageal and Gastric VaricesEsophagitisFemaleGastrointestinal HemorrhageHematemesisHospital MortalityHospitalizationHumansLength of StayMaleMedicaidMedicareMelenaMiddle AgedPeptic UlcerPeptic Ulcer HemorrhageRetreatmentRetrospective StudiesUnited StatesConceptsUpper gastrointestinal bleedingGastrointestinal bleedingCommon causeOutcomes of UGIBVariceal upper gastrointestinal bleedingNonvariceal upper gastrointestinal bleedingCause of bleedingRisk of deathLower socioeconomic patientsUrban US hospitalsErosive esophagitisInpatient mortalityRepeat endoscopyUpper endoscopyConsecutive patientsClinical outcomesPeptic ulcerMean ageMedical CenterUrban hospitalPatientsUS hospitalsMultivariate analysisHematemesisEndoscopy
2013
Natural history of acute upper GI bleeding due to tumours: short‐term success and long‐term recurrence with or without endoscopic therapy
Sheibani S, Kim JJ, Chen B, Park S, Saberi B, Keyashian K, Buxbaum J, Laine L. Natural history of acute upper GI bleeding due to tumours: short‐term success and long‐term recurrence with or without endoscopic therapy. Alimentary Pharmacology & Therapeutics 2013, 38: 144-150. PMID: 23710797, DOI: 10.1111/apt.12347.Peer-Reviewed Original ResearchConceptsUpper gastrointestinal bleedingEndoscopic therapyHaemodynamic instabilityMalignant tumorsBiopsy-proven malignant tumorsAcute upper GISubstantial blood lossLong-term recurrenceYears of ageInitial haemostasisRepeat hospitalisationActive bleedingGastrointestinal bleedingIndex hospitalisationEndoscopic findingsMetastatic diseaseUpper endoscopyBlood lossConsecutive patientsEndoscopic treatmentUpper GIEndoscopy databaseRisk factorsPatientsMultivariate analysis
2012
Management of Patients With Ulcer Bleeding
Laine L, Jensen DM. Management of Patients With Ulcer Bleeding. The American Journal Of Gastroenterology 2012, 107: 345. PMID: 22310222, DOI: 10.1038/ajg.2011.480.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsBlood TransfusionClinical Trials as TopicEndoscopy, GastrointestinalErythromycinEvidence-Based MedicineFluid TherapyGastric LavageHemostasis, EndoscopicHumansMeta-Analysis as TopicPatient SelectionPeptic Ulcer HemorrhagePrognosisProton Pump InhibitorsResuscitationRetreatmentRisk AssessmentSecondary PreventionConceptsNonsteroidal anti-inflammatory drugsAnti-ulcer therapyEndoscopic therapyHemodynamic statusCOX-2-selective nonsteroidal anti-inflammatory drugsNon-bleeding visible vesselOvert upper gastrointestinal bleedingDirect further managementSecond endoscopic treatmentStep-wise managementUpper gastrointestinal bleedingManagement of patientsProton pump inhibitorsAnti-inflammatory drugsIdiopathic ulcersPPI therapyActive bleedingGastrointestinal bleedingRecurrent bleedingUlcer bleedingEndoscopic featuresFirst endoscopyUpper endoscopyAdherent clotEndoscopic treatment
2010
Randomized Trial of Urgent vs. Elective Colonoscopy in Patients Hospitalized With Lower GI Bleeding
Laine L, Shah A. Randomized Trial of Urgent vs. Elective Colonoscopy in Patients Hospitalized With Lower GI Bleeding. The American Journal Of Gastroenterology 2010, 105: 2636. PMID: 20648004, DOI: 10.1038/ajg.2010.277.Peer-Reviewed Original ResearchConceptsLower GI bleedingElective colonoscopyUpper endoscopyUrgent colonoscopyGI bleedingBlood pressureHeart rateUpper gastrointestinal sourceUpper GI sourceUrgent upper endoscopyPrimary end pointDuration of hospitalizationSystolic blood pressureUnits of bloodEligible patientsUrgent groupElective groupHospital daysOrthostatic changesBlood transfusionClinical outcomesRandomized trialsHospital chargesVs. 5Gastrointestinal sourceDoes Capsule Endoscopy Improve Outcomes in Obscure Gastrointestinal Bleeding? Randomized Trial Versus Dedicated Small Bowel Radiography
Laine L, Sahota A, Shah A. Does Capsule Endoscopy Improve Outcomes in Obscure Gastrointestinal Bleeding? Randomized Trial Versus Dedicated Small Bowel Radiography. Gastroenterology 2010, 138: 1673-1680.e1. PMID: 20138043, DOI: 10.1053/j.gastro.2010.01.047.Peer-Reviewed Original ResearchConceptsObscure GI bleedingObscure gastrointestinal bleedingDiagnostic yieldGI bleedingGastrointestinal bleedingTherapeutic interventionsCapsule endoscopyNegative upper endoscopySubsequent blood transfusionSmall bowel radiographyOccult bleedingPrimary endpointSubsequent hospitalizationMost patientsUpper endoscopyBlood transfusionHemoglobin levelsRandomized trialsVs 5Improved outcomesBleedingContrast radiographyPatientsEndoscopyAbstractText
1998
Evaluation of the FlexSure HP whole blood antibody test for diagnosis of Helicobacter pylori infection
Sadowski D, Cohen H, Laine L, Greenberg P, Goldstein J, Mihalov M, Cutler A. Evaluation of the FlexSure HP whole blood antibody test for diagnosis of Helicobacter pylori infection. The American Journal Of Gastroenterology 1998, 93: ajg1998490. PMID: 9820383, DOI: 10.1111/j.1572-0241.1998.00604.x.Peer-Reviewed Original ResearchConceptsHelicobacter pylori infectionRapid urease testPylori infectionWhole blood testH. pyloriWhole bloodBlood testsUrease testPositive rapid urease testBlood antibody testH. pylori infectionProton pump inhibitorsH. pylori diagnosisDetection of antibodiesUpper endoscopyStudy enrollmentPump inhibitorsGastric biopsiesIgG antibodiesSerum testAntibody testOffice testsAntral tissueBacterial infectionsPatients
1993
Protein-losing enteropathy and hypoalbuminemia in AIDS
Laine L, Garcia F, McGilligan K, Malinko A, Sinatra F, Thomas D. Protein-losing enteropathy and hypoalbuminemia in AIDS. AIDS 1993, 7: 837-840. PMID: 8363760, DOI: 10.1097/00002030-199306000-00012.Peer-Reviewed Original ResearchConceptsNormal bowel habitsProtein-losing enteropathyFecal alphaBowel habitsNormal serum albuminNormal albuminFecal alpha 1Normal albumin groupUrban county hospitalGroup of patientsDevelopment of hypoalbuminemiaUpper endoscopyFlexible sigmoidoscopyAlbumin groupMucosal diseaseCounty HospitalHypoalbuminemiaMAIN OUTCOMEProspective assessmentSerum albuminPatientsLinear regression analysisDiarrheaSignificant negative correlationGross abnormalities
1988
Histology of alcoholic hemorrhagic “gastritis”: A prospective evaluation
Laine L, Weinstein W. Histology of alcoholic hemorrhagic “gastritis”: A prospective evaluation. Gastroenterology 1988, 94: 1254-1262. PMID: 3258836, DOI: 10.1016/0016-5085(88)90661-0.Peer-Reviewed Original ResearchConceptsSubepithelial hemorrhageAlcoholic patientsHemorrhagic gastritisBiopsy specimensProminent inflammatory cell infiltrationFoveolar regionInflammatory cell infiltrateInflammatory cell infiltrationGastrointestinal bleedingUpper endoscopyCell infiltrateMucosal edemaProspective evaluationAdjacent mucosaBarrett's esophagusCell infiltrationGastric biopsiesHemorrhagic lesionsTarget lesionsHistologic natureHemorrhage scoreHistologic scoringBiopsy siteHemorrhagePatients