2010
Randomized Trial of Urgent vs. Elective Colonoscopy in Patients Hospitalized With Lower GI Bleeding
Laine L, Shah A. Randomized Trial of Urgent vs. Elective Colonoscopy in Patients Hospitalized With Lower GI Bleeding. The American Journal Of Gastroenterology 2010, 105: 2636. PMID: 20648004, DOI: 10.1038/ajg.2010.277.Peer-Reviewed Original ResearchConceptsLower GI bleedingElective colonoscopyUpper endoscopyUrgent colonoscopyGI bleedingBlood pressureHeart rateUpper gastrointestinal sourceUpper GI sourceUrgent upper endoscopyPrimary end pointDuration of hospitalizationSystolic blood pressureUnits of bloodEligible patientsUrgent groupElective groupHospital daysOrthostatic changesBlood transfusionClinical outcomesRandomized trialsHospital chargesVs. 5Gastrointestinal source
1990
Multipolar electrocoagulation versus injection therapy in the treatment of bleeding peptic ulcers A prospective, randomized trial
Laine L. Multipolar electrocoagulation versus injection therapy in the treatment of bleeding peptic ulcers A prospective, randomized trial. Gastroenterology 1990, 99: 1303-1306. PMID: 2210238, DOI: 10.1016/0016-5085(90)91154-x.Peer-Reviewed Original ResearchConceptsNonbleeding visible vesselMultipolar electrocoagulationInjection therapyVisible vesselEndoscopic evidenceActive bleedingBloody nasogastric aspirateUpper gastrointestinal bleedHigh-risk patientsUnstable vital signsIncidence of surgeryTreatment of patientsCost of hospitalizationUnits of bloodFurther bleedingGastrointestinal bleedHospital stayNasogastric aspirateClinical evidencePeptic ulcerComparable efficacyMortality ratePatientsBleedingUlcers
1989
Multipolar electrocoagulation in the treatment of peptic ulcers with nonbleeding visible vessels. A prospective, controlled trial.
Laine L. Multipolar electrocoagulation in the treatment of peptic ulcers with nonbleeding visible vessels. A prospective, controlled trial. Annals Of Internal Medicine 1989, 110: 510-4. PMID: 2647014, DOI: 10.7326/0003-4819-110-7-510.Peer-Reviewed Original ResearchConceptsNonbleeding visible vesselMultipolar electrocoagulationVisible vesselControl groupMajor upper gastrointestinal hemorrhageMean transfusion requirementSham-controlled trialUpper gastrointestinal hemorrhageUnstable vital signsSafety of treatmentCost of hospitalizationUnits of bloodEndoscopic evidenceGastrointestinal hemorrhageTransfusion requirementsUrgent surgeryEmergency surgeryHospital daysEndoscopic treatmentOverall mortalityPeptic ulcerCounty HospitalAspirate samplesDiagnostic endoscopyTreatment groups
1987
Multipolar Electrocoagulation in the Treatment of Active Upper Gastrointestinal Tract Hemorrhage
Laine L. Multipolar Electrocoagulation in the Treatment of Active Upper Gastrointestinal Tract Hemorrhage. New England Journal Of Medicine 1987, 316: 1613-1617. PMID: 3295547, DOI: 10.1056/nejm198706253162601.Peer-Reviewed Original ResearchConceptsUpper gastrointestinal tract hemorrhageUpper gastrointestinal hemorrhageGastrointestinal tract hemorrhageMultipolar electrocoagulationGastrointestinal hemorrhageTract hemorrhageActive upper gastrointestinal hemorrhageNonvariceal upper gastrointestinal hemorrhageBloody nasogastric aspirateTerms of hemostasisMallory-Weiss tearUnstable vital signsUnits of bloodTransfusion requirementsActive bleedingHospital courseEmergency surgeryHospital daysNasogastric aspirateNonsurgical therapyVascular malformationsMean costHemorrhagePatientsVital signs