2019
Validation of a Machine Learning Model That Outperforms Clinical Risk Scoring Systems for Upper Gastrointestinal Bleeding
Shung DL, Au B, Taylor RA, Tay JK, Laursen SB, Stanley AJ, Dalton HR, Ngu J, Schultz M, Laine L. Validation of a Machine Learning Model That Outperforms Clinical Risk Scoring Systems for Upper Gastrointestinal Bleeding. Gastroenterology 2019, 158: 160-167. PMID: 31562847, PMCID: PMC7004228, DOI: 10.1053/j.gastro.2019.09.009.Peer-Reviewed Original ResearchConceptsUpper gastrointestinal bleedingHospital-based interventionsComposite endpointScoring systemRockall scoreGastrointestinal bleedingClinical riskConsecutive unselected patientsLow-risk patientsClinical scoring systemRisk-scoring systemExternal validation cohortCharacteristic curve analysisInternal validation setOutpatient managementUnselected patientsValidation cohortEmergency departmentMedical CenterGreater AUCPatientsAbstractTextCurve analysisEndpointAUC
2017
Predictors and outcomes of delayed plastic biliary stent removal following endoscopic retrograde cholangiopancreatography
Kim SJ, Ohanian E, Lee F, Nam B, Che K, Laine L, Kim SE, Kim JJ. Predictors and outcomes of delayed plastic biliary stent removal following endoscopic retrograde cholangiopancreatography. Scandinavian Journal Of Gastroenterology 2017, 52: 1128-1132. PMID: 28657377, DOI: 10.1080/00365521.2017.1342138.Peer-Reviewed Original ResearchConceptsEndoscopic retrograde cholangiopancreatographyBiliary stent removalBiliary stent placementStent removalStent obstructionRetrograde cholangiopancreatographyStent placementIndex endoscopic retrograde cholangiopancreatographyNon-English primary languageOutcomes of patientsOutpatient endoscopic retrograde cholangiopancreatographyPreventable adverse eventsMultivariable regression analysisUniversity Medical CenterPlastic biliary stentsAnesthesia assistanceBaseline characteristicsAdverse eventsConsecutive patientsClinical outcomesLoma Linda University Medical CenterOne-fifthMedical CenterBiliary stentsLower odds
2016
Yield of repeat forward-view examination of the right side of the colon in screening and surveillance colonoscopy
Clark BT, Parikh ND, Laine L. Yield of repeat forward-view examination of the right side of the colon in screening and surveillance colonoscopy. Gastrointestinal Endoscopy 2016, 84: 126-132. PMID: 26769408, PMCID: PMC4912931, DOI: 10.1016/j.gie.2015.12.030.Peer-Reviewed Original ResearchConceptsAdenoma detection rateForward-view examinationOverall adenoma detection rateSecond examinationRight sideSurveillance colonoscopyAdditional adenomasWest Haven Veterans Affairs Medical CenterVeterans Affairs Medical CenterBoston Bowel Preparation Scale scoreDistal colon cancerNumber of patientsYears of ageDevelopment of cancerSecondary outcomesPrimary outcomeMen 50Prospective studySurveillance intervalsAdenoma detectionDetection rateMedical CenterInitial examinationPatientsColon cancer
2015
Quantification of Adequate Bowel Preparation for Screening or Surveillance Colonoscopy in Men
Clark BT, Protiva P, Nagar A, Imaeda A, Ciarleglio MM, Deng Y, Laine L. Quantification of Adequate Bowel Preparation for Screening or Surveillance Colonoscopy in Men. Gastroenterology 2015, 150: 396-405. PMID: 26439436, PMCID: PMC4728019, DOI: 10.1053/j.gastro.2015.09.041.Peer-Reviewed Original ResearchConceptsAdequate bowel preparationBBPS scoreSurveillance colonoscopyBowel preparationColon segmentsBBPS scoresSecond examinationWest Haven Veterans Affairs Medical CenterVeterans Affairs Medical CenterFirst examinationGuideline-recommended intervalsProspective observational studyDetection of adenomasIdentification of polypsColonoscopic evaluationPrimary outcomeSurveillance intervalsBlinded endoscopistsColonoscopy examinationObservational studyPrEP scaleMedical CenterInitial examinationStudy subjectsAdequate preparation
2014
Causes of Bleeding and Outcomes in Patients Hospitalized With Upper Gastrointestinal Bleeding
Kim JJ, Sheibani S, Park S, Buxbaum J, Laine L. Causes of Bleeding and Outcomes in Patients Hospitalized With Upper Gastrointestinal Bleeding. Journal Of Clinical Gastroenterology 2014, 48: 113-118. PMID: 23685847, DOI: 10.1097/mcg.0b013e318297fb40.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overEndoscopy, GastrointestinalEsophageal and Gastric VaricesEsophagitisFemaleGastrointestinal HemorrhageHematemesisHospital MortalityHospitalizationHumansLength of StayMaleMedicaidMedicareMelenaMiddle AgedPeptic UlcerPeptic Ulcer HemorrhageRetreatmentRetrospective StudiesUnited StatesConceptsUpper gastrointestinal bleedingGastrointestinal bleedingCommon causeOutcomes of UGIBVariceal upper gastrointestinal bleedingNonvariceal upper gastrointestinal bleedingCause of bleedingRisk of deathLower socioeconomic patientsUrban US hospitalsErosive esophagitisInpatient mortalityRepeat endoscopyUpper endoscopyConsecutive patientsClinical outcomesPeptic ulcerMean ageMedical CenterUrban hospitalPatientsUS hospitalsMultivariate analysisHematemesisEndoscopy
2013
The yield and cost of colonoscopy in patients with metastatic cancer of unknown primary
Saliminejad M, Bemanian S, Ho A, Spiegel B, Laine L. The yield and cost of colonoscopy in patients with metastatic cancer of unknown primary. Alimentary Pharmacology & Therapeutics 2013, 38: 628-633. PMID: 23869398, DOI: 10.1111/apt.12429.Peer-Reviewed Original ResearchConceptsPrimary colon cancerCost of colonoscopyColon cancerColon primaryUnknown primaryMetastatic cancerVeterans Administration Medical CenterPalpable rectal massPrior colon cancerIron deficiency anemiaOccult bleedingAdvanced diseaseRectal massStandard indicationsDiagnostic colonoscopyEnrollment criteriaRoutine colonoscopyTargeted therapyColorectal lesionsMedical CenterExclusion criteriaColonoscopyPatientsCancer syndromesCancer
1984
Recurrent Pericarditis and Celiac Disease
Laine L, Holt K. Recurrent Pericarditis and Celiac Disease. JAMA 1984, 252: 3168-3168. PMID: 6502887, DOI: 10.1001/jama.1984.03350220074036.Peer-Reviewed Case Reports and Technical NotesConceptsPleuritic chest painRecurrent pericarditisCeliac diseaseChest painIdiopathic pericarditisPericardial rubLeft-sided pleuritic chest painSan Diego Veterans Administration Medical CenterVeterans Administration Medical CenterDiffuse ST elevationAnti-inflammatory medicationsCurable causeChest roentgenogramTreatable causePleural effusionST elevationMedical CenterPericarditisPainDiseaseCommon formPatientsRecent reportsThorough evaluationCause