Immunogenicity of ferroptosis in cancer: a matter of context?
Catanzaro E, Demuynck R, Naessens F, Galluzzi L, Krysko D. Immunogenicity of ferroptosis in cancer: a matter of context? Trends In Cancer 2024, 10: 407-416. PMID: 38368244, DOI: 10.1016/j.trecan.2024.01.013.Peer-Reviewed Original ResearchTumor-targeting immune responsesImmune responseCancer cellsKill malignant cellsAdaptive immune responsesInduction of ferroptosisImmunogenicity of ferroptosisAnticancer immunityMicroenvironmental defectMalignant cellsImmune cellsPlasma membrane breakdownFerroptosis inducersNecrotic formCell deathFerroptosisImbalance of cellular redox homeostasisLipid peroxidationCellsMembrane breakdownCellular redox homeostasisRedox homeostasisContext-dependent effectsImmunogenicityAdjuvanticity