2022
Comparison of a dichotomous versus trichotomous checklist for neonatal intubation
Johnston L, Sawyer T, Nishisaki A, Whitfill T, Ades A, French H, Glass K, Dadiz R, Bruno C, Levit O, Auerbach M. Comparison of a dichotomous versus trichotomous checklist for neonatal intubation. BMC Medical Education 2022, 22: 645. PMID: 36028871, PMCID: PMC9419414, DOI: 10.1186/s12909-022-03700-4.Peer-Reviewed Original ResearchMeSH KeywordsChecklistClinical CompetenceFeedbackHumansInfant, NewbornIntubation, IntratrachealReproducibility of ResultsImpact of multiple intubation attempts on adverse tracheal intubation associated events in neonates: a report from the NEAR4NEOS
Singh N, Sawyer T, Johnston LC, Herrick HM, Moussa A, Zenge J, Jung P, DeMeo S, Glass K, Howlett A, Shults J, Barry J, Brei BK, Kim JH, Quek BH, Tingay D, Mehrem AA, Napolitano N, Nishisaki A, Foglia EE. Impact of multiple intubation attempts on adverse tracheal intubation associated events in neonates: a report from the NEAR4NEOS. Journal Of Perinatology 2022, 42: 1221-1227. PMID: 35982243, DOI: 10.1038/s41372-022-01484-5.Peer-Reviewed Original ResearchConceptsIntubation attemptsNational Emergency Airway RegistryAdverse tracheal intubationClinical adverse outcomesDesignA retrospective studySevere oxygen desaturationMultiple intubation attemptsTracheal intubation attemptsAdverse safety eventsAirway RegistryOxygen desaturationAdverse eventsRetrospective studyTracheal intubationAdverse outcomesDelivery roomOdds ratioNeonatal intubationHigh riskTI attemptsAcademic centersIntubationSafety eventsNumber of attemptsNeonatesDoes videolaryngoscopy improve tracheal intubation first attempt success in the NICUs? A report from the NEAR4NEOS
Moussa A, Sawyer T, Puia-Dumitrescu M, Foglia EE, Ades A, Napolitano N, Glass KM, Johnston L, Jung P, Singh N, Quek BH, Barry J, Zenge J, DeMeo S, Mehrem AA, Nadkarni V, Nishisaki A. Does videolaryngoscopy improve tracheal intubation first attempt success in the NICUs? A report from the NEAR4NEOS. Journal Of Perinatology 2022, 42: 1210-1215. PMID: 35922664, PMCID: PMC9362392, DOI: 10.1038/s41372-022-01472-9.Peer-Reviewed Original ResearchHumansInfant, NewbornIntensive Care Units, NeonatalIntubation, IntratrachealLaryngoscopesLaryngoscopyRegistries
2021
Intubation Competence During Neonatal Fellowship Training
Evans P, Shults J, Weinberg DD, Napolitano N, Ades A, Johnston L, Levit O, Brei B, Krick J, Sawyer T, Glass K, Wile M, Hollenberg J, Rumpel J, Moussa A, Verreault A, Mehrem A, Howlett A, McKanna J, Nishisaki A, Foglia EE. Intubation Competence During Neonatal Fellowship Training. Pediatrics 2021, 148: e2020036145. PMID: 34172556, PMCID: PMC8290971, DOI: 10.1542/peds.2020-036145.Peer-Reviewed Original ResearchMeSH KeywordsCanadaClinical CompetenceFellowships and ScholarshipsHumansInfant, NewbornIntubation, IntratrachealMultivariate AnalysisRegistriesRetrospective StudiesUnited StatesConceptsIntubation encountersFellowship trainingNational Emergency Airway RegistryMulti-center cohort studyNorth American academic centersNeonatal-perinatal medicine fellowsNumber of intubationsOverall success rateCumulative sum analysisProcedural competenceAirway RegistryCohort studyMultivariable analysisIntubation attemptsNeonatal intubationSuccessful intubationIntubation successAcademic centersIndividualized approachPractice characteristicsStart of trainingIntubationProgressionIndependent impactSuccess rateImpact of Physician Training Level on Neonatal Tracheal Intubation Success Rates and Adverse Events: A Report from National Emergency Airway Registry for Neonates (NEAR4NEOS)
Johnston L, Sawyer T, Ades A, Moussa A, Zenge J, Jung P, DeMeo S, Glass K, Singh N, Howlett A, Shults J, Barry J, Brei B, Foglia E, Nishisaki A. Impact of Physician Training Level on Neonatal Tracheal Intubation Success Rates and Adverse Events: A Report from National Emergency Airway Registry for Neonates (NEAR4NEOS). Neonatology 2021, 118: 434-442. PMID: 34111869, PMCID: PMC8376802, DOI: 10.1159/000516372.Peer-Reviewed Original ResearchMeSH KeywordsChildEducational StatusHumansInfant, NewbornIntubation, IntratrachealPhysiciansProspective StudiesRegistriesConceptsPhysician training levelFirst-attempt successOxygen desaturationAdverse eventsMultivariable analysisNeonatal physiciansNational Emergency Airway RegistryTracheal intubation success rateFirst-attempt success rateSevere oxygen desaturationProspective cohort studyIntubation success rateSuccess rateTraining levelAirway RegistryCohort studyPatient ageIntubation outcomesUnivariable analysisIndependent associationOdds ratioPractice characteristicsPrimary TiDesaturationTI successAssociations of Stylet Use during Neonatal Intubation with Intubation Success, Adverse Events, and Severe Desaturation: A Report from NEAR4NEOS
Gray MM, Rumpel JA, Brei BK, Krick JA, Sawyer T, Glass K, DeMeo S, Barry J, Ades A, Napolitano N, Johnston L, Moussa A, Jung P, Quek BH, Mehrem AA, Zenge J, Shults J, Nadkarni V, Kim J, Singh N, Tisnic A, Foglia E, Nishisaki A. Associations of Stylet Use during Neonatal Intubation with Intubation Success, Adverse Events, and Severe Desaturation: A Report from NEAR4NEOS. Neonatology 2021, 118: 470-478. PMID: 33946064, PMCID: PMC8376756, DOI: 10.1159/000515872.Peer-Reviewed Original ResearchMeSH KeywordsChildHumansInfant, NewbornIntensive Care Units, NeonatalIntubation, IntratrachealLogistic ModelsRegistriesConceptsTracheal intubation-associated eventsNeonatal intensive care unitFirst-attempt intubation successSevere desaturationStylet useIntubation successDelivery roomIntubation outcomesOral intubationNeonatal intubationSevere oxygen desaturationIntensive care unitFirst-attempt successGeneralized estimates equationsMainstem intubationOxygen desaturationAdverse eventsCare unitTracheal intubationInternational registryPediatric providersIntubationUnsuccessful first attemptEsophageal intubationLogistic regressionAssociations between family presence and neonatal intubation outcomes: a report from the National Emergency Airway Registry for Neonates: NEAR4NEOS
Brei BK, Sawyer T, Umoren R, Gray MM, Krick J, Foglia EE, Ades A, Glass K, Kim JH, Singh N, Jung P, Johnston L, Moussa A, Napolitano N, Barry J, Zenge J, Quek B, DeMeo SD, Shults J, Unrau J, Nadkarni V, Nishisaki A. Associations between family presence and neonatal intubation outcomes: a report from the National Emergency Airway Registry for Neonates: NEAR4NEOS. Archives Of Disease In Childhood Fetal & Neonatal 2021, 106: 392-397. PMID: 33478956, PMCID: PMC8237190, DOI: 10.1136/archdischild-2020-319709.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unitSevere oxygen desaturationNational Emergency Airway RegistryTracheal intubationOxygen desaturationFamily presenceAirway RegistryIntubation successAcademic neonatal intensive care unitFirst-attempt success rateAdverse tracheal intubationChronic respiratory failureIntensive care unitAttempt success rateFirst-attempt successNeonatal tracheal intubationsRespiratory failureIntubation outcomesCare unitIndependent associationImportant patientAttempt successRetrospective analysisMultivariate analysisOlder infants
2020
Stress as tool or toxin: physiologic markers and subjective report in neonatal simulation
Redmond B, Joseph M, Ray J, Shabanova V, Gross IT, Bruno C, McPadden J, Auerbach M, Johnston L. Stress as tool or toxin: physiologic markers and subjective report in neonatal simulation. Pediatric Research 2020, 88: 784-791. PMID: 32045934, DOI: 10.1038/s41390-020-0806-9.Peer-Reviewed Original Research
2019
Comparison of Neonatal Intubation Practice and Outcomes between the Neonatal Intensive Care Unit and Delivery Room
Herrick HM, Glass KM, Johnston LC, Singh N, Shults J, Ades A, Nadkarni V, Nishisaki A, Foglia EE. Comparison of Neonatal Intubation Practice and Outcomes between the Neonatal Intensive Care Unit and Delivery Room. Neonatology 2019, 117: 65-72. PMID: 31563910, PMCID: PMC7098841, DOI: 10.1159/000502611.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unitFirst-attempt success rateIntensive care unitAttempt success rateTracheal intubationFirst-attempt successDelivery roomUnivariable analysisCare unitAttempt successNational Emergency Airway RegistryAdverse tracheal intubationRetrospective cohort studyNeonatal tracheal intubationsSuccess rateExposure of interestLogistic regression modelsAirway RegistryBaseline characteristicsCohort studySevere desaturationMultivariable analysisIntubation practicesSafety outcomesPractice characteristicsTeam Stress and Adverse Events during Neonatal Tracheal Intubations: A Report from NEAR4NEOS
Umoren RA, Sawyer TL, Ades A, DeMeo S, Foglia EE, Glass K, Gray MM, Barry J, Johnston L, Jung P, Kim JH, Krick J, Moussa A, Mulvey C, Nadkarni V, Napolitano N, Quek BH, Singh N, Zenge JP, Shults J, Nishisaki A. Team Stress and Adverse Events during Neonatal Tracheal Intubations: A Report from NEAR4NEOS. American Journal Of Perinatology 2019, 37: 1417-1424. PMID: 31365934, DOI: 10.1055/s-0039-1693698.Peer-Reviewed Original ResearchConceptsAdverse eventsTracheal intubationAcademic neonatal intensive care unitNeonatal intensive care unitAdverse tracheal intubationIntensive care unitNeonatal tracheal intubationsHemodynamic instabilityOxygenation failureCare unitPotential confoundersNeonatal intubationFamily presenceEvent ratesIntubationPractice factorsHigh stress levelsLikert scaleAssociationTeam stressStress levelsPremedicationLevelsPatientsConfoundersPremedication with neuromuscular blockade and sedation during neonatal intubation is associated with fewer adverse events
Ozawa Y, Ades A, Foglia EE, DeMeo S, Barry J, Sawyer T, Singh N, Glass K, Jung P, Quek BH, Johnston L, Kim J, Napolitano N, Shults J, Nadkarni VM, Nishisaki A. Premedication with neuromuscular blockade and sedation during neonatal intubation is associated with fewer adverse events. Journal Of Perinatology 2019, 39: 848-856. PMID: 30940929, DOI: 10.1038/s41372-019-0367-0.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unitAdverse tracheal intubationTracheal intubationNeuromuscular blockadeNational Emergency Airway RegistryDesignRetrospective cohort studyImpact of premedicationSevere oxygen desaturationIntensive care unitAirway RegistryBlockade groupOxygen desaturationAdverse eventsCohort studyMedication groupCare unitOdds ratioNeonatal intubationSedationBlockadePremedicationIntubationMedicationsStandard useNeonatesIncidence, impact and indicators of difficult intubations in the neonatal intensive care unit: a report from the National Emergency Airway Registry for Neonates
Sawyer T, Foglia EE, Ades A, Moussa A, Napolitano N, Glass K, Johnston L, Jung P, Singh N, Quek BH, Barry J, Zenge J, DeMeo SD, Brei B, Krick J, Kim JH, Nadkarni V, Nishisaki A. Incidence, impact and indicators of difficult intubations in the neonatal intensive care unit: a report from the National Emergency Airway Registry for Neonates. Archives Of Disease In Childhood Fetal & Neonatal 2019, 104: f461. PMID: 30796059, DOI: 10.1136/archdischild-2018-316336.Peer-Reviewed Original ResearchMeSH KeywordsAirway ManagementClinical CompetenceEmergenciesFemaleHumansHypoxiaIncidenceInfant, NewbornInfant, PrematureIntensive Care Units, NeonatalIntubation, IntratrachealMaleOutcome Assessment, Health CarePractice Patterns, Physicians'Quality ImprovementRegistriesRetrospective StudiesUnited StatesConceptsNeonatal intensive care unitNational Emergency Airway RegistrySevere oxygen desaturationIntensive care unitDifficult intubationAirway RegistryOxygen desaturationAdverse eventsCare unitTracheal intubationOdds ratioAcademic neonatal intensive care unitDifficult intubation groupSmall preterm infantsDifficult tracheal intubationIntubation groupPreterm infantsRetrospective reviewClinical impactIntubationNeonatesRegistryIncidenceDesaturationLack of sensitivityNeonatal Intubation Practice and Outcomes: An International Registry Study
Foglia EE, Ades A, Sawyer T, Glass KM, Singh N, Jung P, Quek BH, Johnston LC, Barry J, Zenge J, Moussa A, Kim JH, DeMeo SD, Napolitano N, Nadkarni V, Nishisaki A. Neonatal Intubation Practice and Outcomes: An International Registry Study. Pediatrics 2019, 143: e20180902. PMID: 30538147, PMCID: PMC6317557, DOI: 10.1542/peds.2018-0902.Peer-Reviewed Original ResearchMeSH KeywordsEmergency Medical ServicesFemaleHumansInfantInfant, NewbornIntensive Care, NeonatalInternationalityIntubation, IntratrachealMaleProspective StudiesRegistriesTreatment OutcomeConceptsTracheal intubation-associated eventsDR intubationIntubation safetyAdverse eventsModifiable factorsIntubation practicesAdverse tracheal intubation-associated eventsDesaturation rateNational Emergency Airway RegistryFirst-attempt success rateDelivery room settingInternational registry studySevere oxygen desaturationFuture interventional studiesAttempt success rateMultivariable logistic regressionNeonatal tracheal intubationsAirway RegistryIntubation characteristicsUnivariable testsOxygen desaturationRegistry studyTracheal intubationInterventional studyNeonatal intubation
2018
Neonatal Intubation Competency Assessment Tool: Development and Validation
Johnston L, Sawyer T, Nishisaki A, Whitfill T, Ades A, French H, Glass K, Dadiz R, Bruno C, Levit O, Gangadharan S, Scherzer D, Moussa A, Auerbach M, Network I. Neonatal Intubation Competency Assessment Tool: Development and Validation. Academic Pediatrics 2018, 19: 157-164. PMID: 30103050, DOI: 10.1016/j.acap.2018.07.008.Peer-Reviewed Original ResearchConceptsCompetency assessment toolNeonatal tracheal intubationsGlobal skills assessmentEPA levelsChecklist scoresCormack-Lehane scoreAssessment toolHealth care providersImportant clinical skillTracheal intubationGlottic exposureNeonatal simulatorCare providersGood internal consistencyPatient harmBlinded reviewersDelphi processActivity levelsSimulation-based trainingClinical skillsScoresInternal consistencyChecklist itemsFinal toolSkills assessmentMoving from controversy to consensus: premedication for neonatal intubation
Johnston L, Kwon SH. Moving from controversy to consensus: premedication for neonatal intubation. Journal Of Perinatology 2018, 38: 611-613. PMID: 29930326, DOI: 10.1038/s41372-018-0115-x.Peer-Reviewed Original Research
2017
Improving neonatal intubation safety: A journey of a thousand miles
Sawyer T, Foglia E, Hatch L, Moussa A, Ades A, Johnston L, Nishisaki A. Improving neonatal intubation safety: A journey of a thousand miles. Journal Of Neonatal-Perinatal Medicine 2017, Preprint: 1-7. PMID: 28409758, DOI: 10.3233/npm-171686.Peer-Reviewed Original ResearchConceptsIntubation safetyNeonatal intubationLower first-attempt success rateSuccess rateFirst-attempt success rateSevere oxygen desaturationMultiple intubation attemptsAttempt success rateIntubation success rateQuality improvement effortsPatient safety researchOxygen desaturationAdverse eventsDecrease complicationsEndotracheal tubeIntubation attemptsNeonatal medicineHigh riskDangerous procedureIntubation trainingCommon procedureIntubationComplicationsNeonatesSafety
2014
Utilization of Exploration-Based Learning and Video-Assisted Learning to Teach GlideScope Videolaryngoscopy
Johnston LC, Auerbach M, Kappus L, Emerson B, Zigmont J, Sudikoff SN. Utilization of Exploration-Based Learning and Video-Assisted Learning to Teach GlideScope Videolaryngoscopy. Teaching And Learning In Medicine 2014, 26: 285-291. PMID: 25010241, DOI: 10.1080/10401334.2014.910462.Peer-Reviewed Original ResearchConceptsEndotracheal intubationPediatric critical carePediatric endotracheal intubationSuccessful endotracheal intubationProcedural performancePediatric emergency medicinePediatric airwayProcedural durationGlideScope videolaryngoscopyAirway simulatorCritical carePediatric providersPediatric anesthesiaIntubation procedureAdult airwayGlideScopeDlRandom orderPediatric residentsEmergency medicineLevel of trainingAirway trainersSuccess rateAirwayBaseline success rate
2013
Neonatal intubation performance: Room for improvement in tertiary neonatal intensive care units
Haubner LY, Barry JS, Johnston LC, Soghier L, Tatum PM, Kessler D, Downes K, Auerbach M. Neonatal intubation performance: Room for improvement in tertiary neonatal intensive care units. Resuscitation 2013, 84: 1359-1364. PMID: 23562374, DOI: 10.1016/j.resuscitation.2013.03.014.Peer-Reviewed Original ResearchMeSH KeywordsClinical CompetenceHumansInfant, NewbornIntensive Care Units, NeonatalIntubation, IntratrachealProspective StudiesQuality ImprovementTertiary Care CentersConceptsNeonatal intensive care unitIntensive care unitCare unitPatient factorsSuccess rateTI attemptsVocal cordsLevel III neonatal intensive care unitTertiary neonatal intensive care unitProcedural success rateProcedure success rateProspective descriptive studyStandardized data collection instrumentTI successTracheal intubation performanceRespiratory failureMedian durationCommon indicationPrimary outcomeHigh success rateNeonatal fellowsCommon reasonPatient decompensationLow success rateIntubation performance