2015
The role of gut microbiota in the development of type 1, type 2 diabetes mellitus and obesity
Tai N, Wong FS, Wen L. The role of gut microbiota in the development of type 1, type 2 diabetes mellitus and obesity. Reviews In Endocrine And Metabolic Disorders 2015, 16: 55-65. PMID: 25619480, PMCID: PMC4348024, DOI: 10.1007/s11154-015-9309-0.Peer-Reviewed Original ResearchConceptsGut microbiotaAutoimmune type 1 diabetesType 2 diabetes mellitusInsulin-resistant type 2 diabetesMajor public health concernAltered gut microbiotaDevelopment of T1DType 2 diabetesType 1 diabetesGut microbiota compositionPublic health concernDiabetes mellitusPersistent hyperglycemiaMetabolic disordersRodent modelsMicrobiota compositionType 1ObesityDiabetesHealth concernPotential mechanismsMicrobiotaT2DT1DDisease development
2010
The role of TLR3 in protection of diabetes by PolyI:C in NOD mice (136.31)
Xiang Y, Wen L, Zhou Z, Wong F. The role of TLR3 in protection of diabetes by PolyI:C in NOD mice (136.31). The Journal Of Immunology 2010, 184: 136.31-136.31. DOI: 10.4049/jimmunol.184.supp.136.31.Peer-Reviewed Original ResearchRole of TLR3Adoptive transferProtective effectDiabetes developmentNon-hematopoietic cellsNOD micePoly IYoung WTBone marrow chimera experimentsOnset of diabetesAdoptive transfer modelExpression of TLR3Diabetic wild typeC administrationTLR3Chimera experimentsPolyIMiceRecipientsTreatmentDiabetesDisease developmentExogenous treatmentNODCells