2020
Diagnostic and clinical utility of the wireless motility capsule in children: A study in patients with functional gastrointestinal disorders
Rodriguez L, Heinz N, Colliard K, Amicangelo M, Nurko S. Diagnostic and clinical utility of the wireless motility capsule in children: A study in patients with functional gastrointestinal disorders. Neurogastroenterology & Motility 2020, 33: e14032. PMID: 33184926, DOI: 10.1111/nmo.14032.Peer-Reviewed Original ResearchConceptsWireless motility capsuleColon transitGastrointestinal symptomsCapsule retentionMotility capsuleLower gastrointestinal symptomsRadiopaque marker studiesFunctional gastrointestinal symptomsFunctional gastrointestinal disordersNuclear medicine gastricGastrointestinal motilityGastrointestinal disordersTransit abnormalitiesClinical utilityGastric transitSymptomsLarger studyPatientsInterpretation agreementMarker studiesMotility parametersStudy interpretationCROMSignificant correlationChildren
2012
Clinical Presentation, Response to Therapy, and Outcome of Gastroparesis in Children
Rodriguez L, Irani K, Jiang H, Goldstein AM. Clinical Presentation, Response to Therapy, and Outcome of Gastroparesis in Children. Journal Of Pediatric Gastroenterology And Nutrition 2012, 55: 185-190. PMID: 22228004, DOI: 10.1097/mpg.0b013e318248ed3f.Peer-Reviewed Original ResearchConceptsPediatric gastroparesisPostviral gastroparesisPromotility therapySymptom resolutionClinical featuresMitochondrial dysfunctionYounger ageOutcomes of gastroparesisMore vomitingPromotility drugsAbdominal painClinical presentationMedian timeRetrospective reviewMale sexMean ageEffective therapyGastroparesisVariable symptomatologyMultivariate analysisTherapySymptomsMonthsLonger durationOverall rateEndoscopic intrapyloric injection of botulinum toxin A in the treatment of children with gastroparesis: a retrospective, open-label study
Rodriguez L, Rosen R, Manfredi M, Nurko S. Endoscopic intrapyloric injection of botulinum toxin A in the treatment of children with gastroparesis: a retrospective, open-label study. Gastrointestinal Endoscopy 2012, 75: 302-309. PMID: 22248598, PMCID: PMC3260460, DOI: 10.1016/j.gie.2011.09.042.Peer-Reviewed Original ResearchConceptsOpen-label studyBotulinum toxin APredictive factorsToxin ASingle tertiary care centerLong-term clinical outcomesRefractory gastroparesis symptomsSymptoms of gastroparesisPlacebo-controlled trialTertiary care centerManagement of childrenSingle case reportsTreatment of childrenGastroparesis refractoryGastroparesis symptomsIntrapyloric injectionReported exacerbationsSpastic disordersClinical improvementMedian durationOlder patientsBotulinum injectionMale patientsMedical therapyRetrospective review