2022
Diverting Ileostomy in Children With Functional Constipation
Rodriguez L, Colliard K, Nurko S, Flores A, Buchmiller TL. Diverting Ileostomy in Children With Functional Constipation. Journal Of Pediatric Gastroenterology And Nutrition 2022, 75: 578-583. PMID: 35897140, DOI: 10.1097/mpg.0000000000003579.Peer-Reviewed Original ResearchConceptsFunctional constipationOstomy closurePediatric functional constipationInstitutional review board approvalReview board approvalEnema failureColon motilityFurther surgeryInvasive evaluationRetrospective studySurgical interventionOstomyBoard approvalUseful interventionLarger studyConstipationSuccessful responsePatientsSurgeryChildrenRole of CMDemographicsAssociationInterventionIndications
2018
Thoracoscopic esophagomyotomy for achalasia in the pediatric population: A retrospective cohort study
Duggan EM, Nurko S, Smithers CJ, Rodriguez L, Fox VL, Fishman SJ. Thoracoscopic esophagomyotomy for achalasia in the pediatric population: A retrospective cohort study. Journal Of Pediatric Surgery 2018, 54: 572-576. PMID: 30121126, DOI: 10.1016/j.jpedsurg.2018.07.013.Peer-Reviewed Original ResearchConceptsRetrospective cohort studyThoracoscopic esophagomyotomyPneumatic dilationCohort studyPediatric populationLength of stayInitial symptom reliefInvasive esophagomyotomyPreoperative dilationPostoperative painRecurrent symptomsMucosal injuryLaparoscopic approachSymptom reliefMedian lengthStandard treatmentEndoscopic guidanceOpen procedureEsophagomyotomyRare diseasePatientsAchalasiaEffective procedureDilationFundoplication
2015
High-resolution manometry combined with impedance measurements discriminates the cause of dysphagia in children
Rommel N, Omari TI, Selleslagh M, Kritas S, Cock C, Rosan R, Rodriguez L, Nurko S. High-resolution manometry combined with impedance measurements discriminates the cause of dysphagia in children. European Journal Of Pediatrics 2015, 174: 1629-1637. PMID: 26105773, DOI: 10.1007/s00431-015-2582-9.Peer-Reviewed Original ResearchConceptsPressure-flow analysisPressure-flow indexGastroesophageal reflux diseaseCause of dysphagiaWeak peristalsisPost-fundoplication dysphagiaHigh-resolution manometryPediatric patientsEsophageal dysfunctionDysphagia symptomsEndoscopic therapyNormal peristalsisOptimal treatmentEsophageal functionClinical practiceTrachea-esophageal fistulaDifferentiation of patientsNon-obstructive dysphagiaPressure flow parametersPediatric clinical practicePressure-flow metricsAdult patientsReflux diseaseEsophageal motilityEsophageal bolus transport
2013
Longitudinal and Radial Characteristics of Intra-Anal Pressures in Children Using 3D High-Definition Anorectal Manometry: New Observations
Ambartsumyan L, Rodriguez L, Morera C, Nurko S. Longitudinal and Radial Characteristics of Intra-Anal Pressures in Children Using 3D High-Definition Anorectal Manometry: New Observations. The American Journal Of Gastroenterology 2013, 108: 1918. PMID: 24169274, DOI: 10.1038/ajg.2013.361.Peer-Reviewed Original ResearchSafety and Efficacy of Cyproheptadine for Treating Dyspeptic Symptoms in Children
Rodriguez L, Diaz J, Nurko S. Safety and Efficacy of Cyproheptadine for Treating Dyspeptic Symptoms in Children. The Journal Of Pediatrics 2013, 163: 261-267. PMID: 23419589, PMCID: PMC3661691, DOI: 10.1016/j.jpeds.2012.12.096.Peer-Reviewed Original ResearchConceptsEfficacy of cyproheptadineDyspeptic symptomsEarly vomitingSide effectsMultivariate analysisRetrospective open-label studyOpen-label studyUpper gastrointestinal symptomsPotent serotonin antagonistUse of cyproheptadineLack of responseLate vomitingAbdominal painGastrointestinal symptomsAntroduodenal manometryFunctional dyspepsiaNissen fundoplicationSerotonin antagonistsFirst therapyGastric emptyingFurther interventionTherapy responseVomitingCyproheptadineResponse rate