Pretreatment level of serum sialic acid predicts both qualitative and quantitative bone metastases of prostate cancer
Sun J, Tian T, Wang N, Jing X, Qiu L, Cui H, Liu Z, Liu J, Yan L, Li D. Pretreatment level of serum sialic acid predicts both qualitative and quantitative bone metastases of prostate cancer. Frontiers In Endocrinology 2024, 15: 1338420. PMID: 38384968, PMCID: PMC10880016, DOI: 10.3389/fendo.2024.1338420.Peer-Reviewed Original ResearchConceptsHigh-volume diseasePresence of bone metastasesSerum sialic acidBone metastasesProstate-specific antigenProstate cancer patientsProstate cancerArea under the curveCut-off valueReceiver operating characteristicAssociated with high volume diseasePredictors of bone metastasisLevels of serum sialic acidClinical parameters of patientsDiagnosis of prostate cancerMetastasis of prostate cancerReceiver operating characteristic curve analysisBone metastasis of prostate cancerDiagnosed PCa patientsMultivariate logistic regression analysisSerum SA levelsMann-Whitney U testParameters of patientsLogistic regression analysisLevels of alkaline phosphatase