2022
In Stroke, When Is a Good Outcome Good Enough?
Schwamm L. In Stroke, When Is a Good Outcome Good Enough? New England Journal Of Medicine 2022, 386: 1359-1361. PMID: 35388672, DOI: 10.1056/nejme2201330.Peer-Reviewed Original ResearchConceptsMechanical thrombectomyRandomized trialsMedical careFavorable resultsThrombectomyStrokeTrialsCare
2017
Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Ischemic Stroke
Yaghi S, Willey JZ, Cucchiara B, Goldstein JN, Gonzales NR, Khatri P, Kim LJ, Mayer SA, Sheth KN, Schwamm LH. Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Ischemic Stroke. Stroke 2017, 48: e343-e361. PMID: 29097489, DOI: 10.1161/str.0000000000000152.Peer-Reviewed Original ResearchConceptsSymptomatic intracranial hemorrhageAcute ischemic strokeIschemic strokeSystemic thrombolysisCase seriesIntravenous thrombolytic therapyMainstay of treatmentSmall case seriesTreatment of patientsBlood-brain barrierWriting group membersHemorrhagic transformationIntravenous alteplaseFeared complicationSevere complicationsPrompt diagnosisRandomized trialsThrombolytic therapyIntracranial hemorrhageRetrospective studyRisk factorsEarly correctionAlteplaseStrokeLiterature review
2010
Rapid Change in Prescribing Behavior in Hospitals Participating in Get With The Guidelines–Stroke After Release of the Management of Atherothrombosis With Clopidogrel in High-Risk Patients (MATCH) Clinical Trial Results
Menon B, Frankel M, Liang L, LaBresh K, Ellrodt G, Hernandez A, Fonarow G, Schwamm L, Smith E. Rapid Change in Prescribing Behavior in Hospitals Participating in Get With The Guidelines–Stroke After Release of the Management of Atherothrombosis With Clopidogrel in High-Risk Patients (MATCH) Clinical Trial Results. Stroke 2010, 41: 2094-2097. PMID: 20634476, DOI: 10.1161/strokeaha.110.584151.Peer-Reviewed Original ResearchConceptsTransient ischemic attackIschemic attackIschemic strokeHigh-risk patients trialAmerican Heart Association Guidelines UpdateManagement of AtherothrombosisPatient clinical trialsGuidelines-StrokeGWTG-StrokeAntithrombotic medicationAntithrombotic therapyStroke ProgramDischarge prescriptionsGuideline updateRandomized trialsConsensus guidelinesHospital characteristicsClinical trialsPrescribing behaviorSustained decreasePatient trialsSustained reductionClinical informationPatientsMatch Study
2004
Virtual TeleStroke Support for the Emergency Department Evaluation of Acute Stroke
Schwamm L, Rosenthal E, Hirshberg A, Schaefer P, Little E, Kvedar J, Petkovska I, Koroshetz W, Levine S. Virtual TeleStroke Support for the Emergency Department Evaluation of Acute Stroke. Academic Emergency Medicine 2004, 11: 1193-1197. PMID: 15528584, DOI: 10.1197/j.aem.2004.08.014.Peer-Reviewed Original ResearchConceptsTissue plasminogen activatorAcute strokeTelestroke consultationNeedle timeSymptom onsetEmergency departmentHealth Stroke Scale scoreIntravenous tissue plasminogen activatorMean National InstitutesPossible acute strokeEmergency department evaluationStroke Scale scoreAcute ischemic strokeEvaluation of patientsEligible patientsStroke neurologistsIschemic strokeDepartment evaluationNeurologic examinationRandomized trialsStroke expertiseProtocol violationsEmergency physiciansInter-rater reliabilityPatient management