2009
Existence of the Diffusion-Perfusion Mismatch within 24 Hours after Onset of Acute Stroke: Dependence on Proximal Arterial Occlusion
Copen W, Rezai Gharai L, Barak E, Schwamm L, Wu O, Kamalian S, Gonzalez R, Schaefer P. Existence of the Diffusion-Perfusion Mismatch within 24 Hours after Onset of Acute Stroke: Dependence on Proximal Arterial Occlusion. Radiology 2009, 250: 878-86. PMID: 19164120, DOI: 10.1148/radiol.2503080811.Peer-Reviewed Original ResearchConceptsProximal arterial occlusionAcute ischemic stroke trialsIschemic stroke trialsAcute strokeArterial occlusionStroke trialsLesion volumePerfusion-weighted magnetic resonance imagesDiffusion-perfusion mismatchMean transit time mapsTransit time mapsHIPAA-compliant studyPAO patientsAngiographic evidenceStroke onsetDose escalationTomographic angiographyEligibility criteriaPatientsInstitutional reviewMagnetic resonance imagesMR angiographyDesmoteplaseSignificant differencesAngiography
2008
An Acute Ischemic Stroke Classification Instrument That Includes CT or MR Angiography: The Boston Acute Stroke Imaging Scale
Torres-Mozqueda F, He J, Yeh I, Schwamm L, Lev M, Schaefer P, González R. An Acute Ischemic Stroke Classification Instrument That Includes CT or MR Angiography: The Boston Acute Stroke Imaging Scale. American Journal Of Neuroradiology 2008, 29: 1111-1117. PMID: 18467521, PMCID: PMC8118840, DOI: 10.3174/ajnr.a1000.Peer-Reviewed Original ResearchConceptsAlberta Stroke Program Early CT ScoreAcute ischemic strokeMinor stroke groupIschemic strokeMajor strokeMinor strokeStroke groupNoncontrast CTBoston Acute Stroke Imaging ScaleProximal cerebral artery occlusionMR angiographyCerebral artery occlusionLength of hospitalizationClassification instrumentCTA patientsArtery occlusionDischarge dispositionConsecutive patientsParenchymal ischemiaCT scorePatient outcomesStroke survivorsRehabilitation facilityPatientsStroke
1998
Regional Ischemia and Ischemic Injury in Patients With Acute Middle Cerebral Artery Stroke as Defined by Early Diffusion-Weighted and Perfusion-Weighted MRI
Rordorf G, Koroshetz W, Copen W, Cramer S, Schaefer P, Budzik R, Schwamm L, Buonanno F, Sorensen A, Gonzalez G. Regional Ischemia and Ischemic Injury in Patients With Acute Middle Cerebral Artery Stroke as Defined by Early Diffusion-Weighted and Perfusion-Weighted MRI. Stroke 1998, 29: 939-943. PMID: 9596239, DOI: 10.1161/01.str.29.5.939.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultAgedAged, 80 and overArterial Occlusive DiseasesBrain IschemiaCerebral ArteriesCerebral InfarctionCerebrovascular CirculationCerebrovascular DisordersDiffusionFemaleHumansMagnetic Resonance AngiographyMagnetic Resonance ImagingMaleMiddle AgedPerfusionReperfusion InjuryConceptsPerfusion-weighted imagingMiddle cerebral artery strokeDiffusion-weighted imagingCerebral blood volumeMCA strokeArtery strokeMR angiographyCBV abnormalityRegional ischemiaAcute middle cerebral artery strokeInitial diffusion-weighted imagingAcute stroke syndromeDistal branch occlusionDWI lesion volumeInitial DWI lesionMCA stem occlusionGroup 2 patientsMRI techniquesFinal infarct sizeFinal infarct volumeHours of onsetIntravenous contrast bolusAbnormal tissue perfusionProgression of infarctionPerfusion-Weighted MRI