Ex Vivo Lung Perfusion Model to Study Pulmonary Tissue Extracellular Microvesicle Profiles
Vallabhajosyula P, Korutla L, Habertheuer A, Reddy S, Schaufler C, Lasky J, Diamond J, Cantu E. Ex Vivo Lung Perfusion Model to Study Pulmonary Tissue Extracellular Microvesicle Profiles. The Annals Of Thoracic Surgery 2017, 103: 1758-1766. PMID: 28242077, DOI: 10.1016/j.athoracsur.2016.11.074.Peer-Reviewed Original ResearchMeSH KeywordsExtracellular VesiclesHumansLungLung TransplantationMass SpectrometryNanoparticlesPerfusionConceptsEVLP systemWestern blot analysisTransplant groupExtracellular microvesiclesVivo lung perfusion modelTime pointsMarginal donor lungsLung perfusion modelFollowing time pointsTranscription-polymerase chain reactionBlot analysisEV size distributionMarginal lungsNontransplant groupDonor lungsLung recoveryLung perfusionSteen solutionPolymerase chain reactionPulmonary parenchymaEV protein cargoPathologic processesPerfusion modelTissue-specific markersPerfusate exchange