2023
Receipt of opioid use disorder treatments prior to fatal overdoses and comparison to no treatment in Connecticut, 2016–17
Heimer R, Black A, Lin H, Grau L, Fiellin D, Howell B, Hawk K, D'Onofrio G, Becker W. Receipt of opioid use disorder treatments prior to fatal overdoses and comparison to no treatment in Connecticut, 2016–17. Drug And Alcohol Dependence 2023, 254: 111040. PMID: 38043226, PMCID: PMC10872282, DOI: 10.1016/j.drugalcdep.2023.111040.Peer-Reviewed Original ResearchConceptsNon-medication treatmentsRelative riskOpioid overdose deathsIncidence rateMOUD treatmentOverdose deathsOpioid use disorder treatmentResults Incidence ratesRetrospective cohort studyDifferent treatment modalitiesPopulation-level effortsUse disorder treatmentFatal opioid poisoningsCohort studyOpioid poisoningTreatment modalitiesConclusion ExposurePoisoning deathsFatal overdosesTreatment exposureDisorder treatmentDeathTreatmentMethadoneRiskConcordance between controlled substance receipt and post-mortem toxicology in opioid-detected overdose deaths: A statewide analysis
Howell B, Black A, Grau L, Lin H, Greene C, Lee H, Heimer R, Hawk K, D'Onofrio G, Fiellin D, Becker W. Concordance between controlled substance receipt and post-mortem toxicology in opioid-detected overdose deaths: A statewide analysis. Drug And Alcohol Dependence 2023, 244: 109788. PMID: 36738634, PMCID: PMC9975083, DOI: 10.1016/j.drugalcdep.2023.109788.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidBenzodiazepinesControlled SubstancesDrug OverdoseHumansOpiate OverdoseUnited StatesConceptsPost-mortem toxicologyOverdose deathsChief Medical ExaminerBenzodiazepine prescribingBenzodiazepine prescriptionsPrimary outcomePreventable deathsOpioid overdosesOpioidsAddiction servicesBenzodiazepinesMental healthStudy periodDeathMedical examinersConcordanceStatewide analysisSubstantial numberReceiptDaysDepartmentMedicationsToxicologyFentanylPrescribingGeographic and temporal trends in fentanyl-detected deaths in Connecticut, 2009–2019
Lu H, Crawford F, Gonsalves G, Grau L. Geographic and temporal trends in fentanyl-detected deaths in Connecticut, 2009–2019. Annals Of Epidemiology 2023, 79: 32-38. PMID: 36669599, PMCID: PMC10163838, DOI: 10.1016/j.annepidem.2023.01.009.Peer-Reviewed Original Research
2013
Seroprevalence of HIV, hepatitis B virus, and HCV among injection drug users in Connecticut: understanding infection and coinfection risks in a nonurban population.
Akselrod H, Grau LE, Barbour R, Heimer R. Seroprevalence of HIV, hepatitis B virus, and HCV among injection drug users in Connecticut: understanding infection and coinfection risks in a nonurban population. American Journal Of Public Health 2013, 104: 1713-21. PMID: 24134382, PMCID: PMC3990658, DOI: 10.2105/ajph.2013.301357.Peer-Reviewed Original ResearchConceptsInjection drug usersHepatitis B virusDrug use durationSubstance abuse treatmentB virusRisk factorsCriminal justice involvementDrug usersAbuse treatmentAdult injection drug usersSeroprevalence of HIVInjection drug usePotential risk factorsSignificant predictorsUse durationMultiple viral infectionsEffective harm reduction strategiesHarm reduction strategiesJustice involvementHCV seroprevalenceInjection useInterim analysisViral infectionDrug useSerological tests
2010
Epidemiologic trends and geographic patterns of fatal opioid intoxications in Connecticut, USA: 1997–2007
Green TC, Grau LE, Carver HW, Kinzly M, Heimer R. Epidemiologic trends and geographic patterns of fatal opioid intoxications in Connecticut, USA: 1997–2007. Drug And Alcohol Dependence 2010, 115: 221-228. PMID: 21131140, PMCID: PMC3095753, DOI: 10.1016/j.drugalcdep.2010.11.007.Peer-Reviewed Original ResearchConceptsPrescription opioidsOpioid typeIntoxication deathsRisk factorsDrug intoxication deathsHeroin-related deathsOpioid-related deathsFatal opioid overdoseChief Medical ExaminerOpioid intoxicationOpioid deathsDrug poisoningInjury deathsEpidemiologic trendsOpioid overdoseOpioidsDeath locationPrevention effortsDeathMedical examinersRegression analysisSignificant increasePublic healthEpidemiologyHeroin[The study of characteristics of overdose among users of opioid drug injections].
Iliuk R, Krupitskiĭ E, Torban M, Kozlov A, Blinnikova K, Heimer R, Green T, Grau L. [The study of characteristics of overdose among users of opioid drug injections]. S S Korsakov Journal Of Neurology And Psychiatry 2010, 110: 33-43. PMID: 21322146.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnalgesics, OpioidDrug OverdoseFemaleHumansInjectionsMaleOpioid-Related DisordersYoung AdultConceptsOpioid overdose riskMore health problemsNonfatal overdosesRole of alcoholDrug injectionOverdose riskEarly diagnosisComorbid disordersOverdose preventionSomatic disordersHealth problemsOverdoseLonger abstinenceMental disordersOverdose situationsDeath casesDisordersSufficient helpOverdosesAdditional predictorsFamily psychotherapyDrug qualityHigher numberDiagnosisAbstinence
2008
Social and structural aspects of the overdose risk environment in St. Petersburg, Russia
Green TC, Grau LE, Blinnikova KN, Torban M, Krupitsky E, Ilyuk R, Kozlov A, Heimer R. Social and structural aspects of the overdose risk environment in St. Petersburg, Russia. International Journal Of Drug Policy 2008, 20: 270-276. PMID: 18774283, PMCID: PMC2696401, DOI: 10.1016/j.drugpo.2008.07.002.Peer-Reviewed Original ResearchConceptsDrug usersRisk behaviorsIntervention feasibilityOpioid overdosesModerate-risk behaviorAbstinence-based treatmentMost drug usersOpioid injectorsSuboptimal responseOverdose response trainingTreatment modalitiesCommon causeOverdose riskNaloxone distributionOverdose mortalityModifiable aspectsAmbulance staffRisk environmentOverdosesTreatment providersMortalityStructural interventionsKey informant interviewsMore ambulancesIntervention