A critical role for NF-κB in Gata3 expression and TH2 differentiation in allergic airway inflammation
Das J, Chen C, Yang L, Cohn L, Ray P, Ray A. A critical role for NF-κB in Gata3 expression and TH2 differentiation in allergic airway inflammation. Nature Immunology 2001, 2: 45-50. PMID: 11135577, DOI: 10.1038/83158.Peer-Reviewed Original ResearchConceptsAllergic airway inflammationT helper 2GATA-3 expressionTh2 differentiationAirway inflammationGATA3 expressionAirway eosinophilic inflammationTh2 cytokine productionT-bet expressionInterferon-γ ProductionTh2 cell recruitmentTranscription factor GATA-3NF-κB activityNuclear factor κBT cell receptorEosinophilic inflammationHelper 2Asthma pathogenesisCytokine productionIL-13IL-5Th2 cellsT cellsInterleukin-4Cell recruitment