Molecular classification of breast cancer: implications for selection of adjuvant chemotherapy
Andre F, Pusztai L. Molecular classification of breast cancer: implications for selection of adjuvant chemotherapy. Nature Reviews Clinical Oncology 2006, 3: 621-632. PMID: 17080180, DOI: 10.1038/ncponc0636.Peer-Reviewed Original ResearchConceptsAdjuvant chemotherapyMolecular classificationBreast cancerER-positive tumorsEarly-stage diseaseNew molecular classificationRoutine clinical useAdjuvant therapyNegative diseaseEstrogen receptorIndividual patientsChemotherapyClinical usePatientsCancerDiseaseMolecular characteristicsFuture promiseTherapyTumorsReceptorsMolecular Classification of Breast Cancer: Limitations and Potential
Pusztai L, Mazouni C, Anderson K, Wu Y, Symmans WF. Molecular Classification of Breast Cancer: Limitations and Potential. The Oncologist 2006, 11: 868-877. PMID: 16951390, DOI: 10.1634/theoncologist.11-8-868.Peer-Reviewed Original ResearchConceptsBreast cancerMolecular classificationNovel risk stratification methodsEstrogen receptor immunohistochemistryBreast cancer patientsRisk stratification methodsRoutine diagnostic workupTranscription-polymerase chain reactionNew molecular classificationReceptor immunohistochemistryCancer patientsDiagnostic workupPolymerase chain reactionBest therapyMolecular subsetsPredictive valueClinical researchCancerDiagnostic testsPredictive testChain reactionMedical decisions