2017
The medically managed patient with severe symptomatic aortic stenosis in the TAVR era: Patient characteristics, reasons for medical management, and quality of shared decision making at heart valve treatment centers
Dharmarajan K, Foster J, Coylewright M, Green P, Vavalle JP, Faheem O, Huang PH, Krishnaswamy A, Thourani VH, McCoy LA, Wang TY. The medically managed patient with severe symptomatic aortic stenosis in the TAVR era: Patient characteristics, reasons for medical management, and quality of shared decision making at heart valve treatment centers. PLOS ONE 2017, 12: e0175926. PMID: 28430791, PMCID: PMC5400246, DOI: 10.1371/journal.pone.0175926.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementPhysician-reported reasonsSevere symptomatic aortic stenosisSymptomatic aortic stenosisAortic valve replacementMedical managementAortic stenosisTreatment centersPatient characteristicsValve replacementTreatment optionsPatient preferencesTreatment decisionsInadequate vascular accessSevere symptomatic ASMedical record reviewFinal treatment decisionSurvey of patientsExperience of careSymptomatic ASTAVR eraRecord reviewVascular accessThirty-day
2016
Coronary Catheterization and Percutaneous Coronary Intervention in China: 10-Year Results From the China PEACE-Retrospective CathPCI Study
Zheng X, Curtis JP, Hu S, Wang Y, Yang Y, Masoudi FA, Spertus JA, Li X, Li J, Dharmarajan K, Downing NS, Krumholz HM, Jiang L. Coronary Catheterization and Percutaneous Coronary Intervention in China: 10-Year Results From the China PEACE-Retrospective CathPCI Study. JAMA Internal Medicine 2016, 176: 512. PMID: 26974883, PMCID: PMC5459379, DOI: 10.1001/jamainternmed.2016.0166.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAngina, UnstableCardiac CatheterizationChinaCoronary Artery DiseaseDrug-Eluting StentsFemaleHospital MortalityHospitals, UrbanHumansLength of StayMaleMedical RecordsMiddle AgedMyocardial InfarctionOdds RatioOutcome Assessment, Health CarePercutaneous Coronary InterventionPostoperative ComplicationsPostoperative HemorrhageQuality of Health CareRetrospective StudiesStentsTime-to-TreatmentConceptsPercutaneous coronary interventionDrug-eluting stentsQuality of careCoronary catheterizationCoronary interventionNonobstructive coronary artery diseasePrimary percutaneous coronary interventionFuture quality improvement initiativesEvidence-based medicationsOutcomes of patientsCoronary artery diseaseClinical observational studyUse of catheterizationQuality improvement initiativesCalendar year 2001Hospital mortalityArtery diseasePatient characteristicsStable patientsTreatment patternsMedian lengthMean agePCI proceduresMedical recordsObservational study
2014
Readmissions after Hospitalization for Heart Failure, Acute Myocardial Infarction, or Pneumonia among Young and Middle-Aged Adults: A Retrospective Observational Cohort Study
Ranasinghe I, Wang Y, Dharmarajan K, Hsieh AF, Bernheim SM, Krumholz HM. Readmissions after Hospitalization for Heart Failure, Acute Myocardial Infarction, or Pneumonia among Young and Middle-Aged Adults: A Retrospective Observational Cohort Study. PLOS Medicine 2014, 11: e1001737. PMID: 25268126, PMCID: PMC4181962, DOI: 10.1371/journal.pmed.1001737.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMiddle-aged adultsTiming of readmissionHeart failureReadmission ratesAMI cohortReadmission diagnosesHF cohortReadmission riskMyocardial infarctionAge groupsRetrospective observational cohort studyIndex admission diagnosisObservational cohort studySimilar risk patternNon-cardiac diagnosisPneumonia cohortAdmission diagnosisElderly patientsCohort studyPatient characteristicsPrimary outcomePayer statusReadmissionHospitalizationProtocol for the China PEACE (Patient-centered Evaluative Assessment of Cardiac Events) retrospective study of coronary catheterisation and percutaneous coronary intervention
Li J, Dharmarajan K, Li X, Lin Z, Normand SL, Krumholz HM, Jiang L, Group F. Protocol for the China PEACE (Patient-centered Evaluative Assessment of Cardiac Events) retrospective study of coronary catheterisation and percutaneous coronary intervention. BMJ Open 2014, 4: e004595. PMID: 24607563, PMCID: PMC3948460, DOI: 10.1136/bmjopen-2013-004595.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionCoronary catheterisationCoronary interventionPatient characteristicsRetrospective studyCardiovascular diseaseComplications of treatmentCost of hospitalisationMedical record abstractionPatterns of careDiagnostic testing patternsTwo-stage clusterHospital outcomesRecord abstractionChinese healthcare systemStudy protocolCase ascertainmentImproved careCatheterisationProcedural treatmentsHospitalCentral Ethics CommitteeChinese hospitalsPatientsChina National Center
2013
The China Patient-Centered Evaluative Assessment of Cardiac Events (China PEACE) Retrospective Study of Acute Myocardial Infarction
Dharmarajan K, Li J, Li X, Lin Z, Krumholz HM, Jiang L. The China Patient-Centered Evaluative Assessment of Cardiac Events (China PEACE) Retrospective Study of Acute Myocardial Infarction. Circulation Cardiovascular Quality And Outcomes 2013, 6: 732-740. PMID: 24221838, PMCID: PMC4054693, DOI: 10.1161/circoutcomes.113.000441.Peer-Reviewed Original ResearchConceptsChina PEACE-Retrospective AMI StudyAcute myocardial infarctionChina PatientRetrospective studyMyocardial infarctionOutcomes of patientsAMI studyDiagnostic testing patternsCause of deathSite of careCardiac eventsHospital outcomesPatient characteristicsHospital treatmentCardiovascular diseaseCase ascertainmentImproved care