Association of Renin Angiotensin Aldosterone System Inhibitors and Outcomes of Hospitalized Patients With COVID-19
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A, Warren K, Wheeler C, Woolman C, Christie A, Ashley D, Adiga R, Moyer A, Verghese G, Newsome A, Forehand C, Bruning R, Jones T, Sabov M, Zaidi F, Tissavirasingham F, Malipeddi D, Mosier J, Lutrick K, Campbell B, Wilson C, Rivers P, Brinks J, Mongoh M, Gilson B, Armaignac D, Parris D, Zuniga M, Vargas I, Boronat V, Hutton A, Kaur N, Neupane P, Sadule-Rios N, Rojas L, Neupane A, Rivera P, Carlos C, Vincent G, Amin M, Schelle M, Steadham A, Howard C, McBride C, Abraham J, Garner O, Richards K, Collins K, Antony P, Mathew S, Danesh V, Dubrocq G, Davis A, Hammers M, McGahey J, Farris A, Priest E, Korsmo R, Fares L, Skiles K, Shor S, Burns K, Dowell C, Flores M, Newman L, Wilk D, Ettlinger J, Bomar J, Darji H, Arroliga A, Arroliga A, Dowell C, Conzales G, Flores M, Newman L, Wilk D, Ettlinger J, Darji H, Bomar J, Khandhar P, Kring E, Banner-Goodspeed V, Bose S, Kelly L, Joseph M, McGourty M, Capers K, Hoenig B, Karamourtopoulos M, Law A, Kassis E, Walkey A, Waikar S, Garcia M, Colona M, 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D, Regunath H, Camazine M, Geiger G, Njai A, Saad B, Shah F, Chuan B, Rawal S, Piracha M, Tonna J, Levin N, Suslavich K, Tsolinas R, Fica Z, Skidmore C, Stapleton R, Dixon A, Johnson O, Ardren S, Burns S, Raymond A, Gonyaw E, Hodgdon K, Housenger C, Lin B, McQuesten K, Pecott-Grimm H, Sweet J, Ventrone S, Khandelwal N, West T, Caldwell E, Lovelace-Macon L, Garimella N, Dow D, Cheruku S, Chen C, Ahmed F, Deonarine C, Jones A, Preston D, Shaikh M, Chin J, Akhter M, Rahman R, Mulrow M, Wilfong E, Vela K, Khanna A, Harris L, Cusson B, Fowler J, Vaneenenaam D, McKinney G, Udoh I, Johnson K, Lyons P, Michelson A, Haluf S, Lynch L, Nguyen N, Steinberg A, Braus N, Pattan V, Papke J, Jimada I, Mhid N, Chakola S, Sheth K, Ammar A, Ammar M, Lopez V, Dela Cruz C, Khosla A, Gautam S. Association of Renin Angiotensin Aldosterone System Inhibitors and Outcomes of Hospitalized Patients With COVID-19. Critical Care Medicine 2022, 50: e744-e758. PMID: 35894609, PMCID: PMC9469914, DOI: 10.1097/ccm.0000000000005627.Peer-Reviewed Original ResearchConceptsHospitalized COVID-19 patientsAldosterone system inhibitorsAntihypertensive agentsCOVID-19 patientsHigh mortalityHospital mortalitySystem inhibitorsRenin-angiotensin-aldosterone system inhibitorsPrior useCOVID-19Retrospective observational studyCOVID-19 registryHospitalized patientsRAASIsObservational studyPatientsLower mortalityMortalityACEIsHospitalizationARBsMedicationsOutcomesInhibitorsAssociationNeurologic Manifestations of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Hospitalized Patients During the First Year of the COVID-19 Pandemic
Cervantes-Arslanian A, Venkata C, Anand P, Burns J, Ong C, LeMahieu A, Schulte P, Singh T, Rabinstein A, Deo N, Bansal V, Boman K, Garces J, Armaignac D, Christie A, Melamed R, Tarabichi Y, Cheruku S, Khanna A, Denson J, Banner-Goodspeed V, Anderson H, Gajic O, Kumar V, Walkey A, Kashyap R, Mesland J, Henin P, Petre H, Buelens I, Gerard A, Clevenbergh P, Granado R, Mercado J, Vega-Terrazas E, Iturricha-Caceres M, Garza R, Chu E, Chan V, Gavidia O, Pachon F, Sanchez Y, knežević D, Kassas M, Badr M, Tawheed A, Tawheed A, Yahia H, Kantas D, Koulouras V, Pineda E, Guillen G, Soto H, Lizardo A, Kopitkó C, Bencze Á, Méhész I, Gerendai Z, Vadgaonkar G, Ediga R, Basety S, Dammareddy S, Kasumalla P, Segu S, Chakraborty T, Joyce E, Papani S, Kamuram M, Daga M, Agarwal M, Rohtagi I, Cherian A, Parameswaran S, Parthiban M, Doddaga P, Chandra N, Rijhwani P, Jain A, Gupta A, Jaiswal R, Tyagi A, Mathur N, Prabhu M, Jakati V, Petrolwala M, Ladva B, Mohan S, Jyothisree E, Raju U, Manduva J, Kolakani N, Sripathi S, Chaitanya S, Agrawal K, Baghel V, Patel K, Dalili N, Nafa M, Matsuda W, Suzuki R, Kyo M, Tahara S, Hayakawa M, Maekawa K, Suzuki R, Sanui M, Horikita S, Itagaki Y, Kodate A, Suzuki R, Kodate A, Takahashi Y, Moriki K, Shiga T, Iwasaki Y, Shigemitsu H, Mishima Y, Nosaka N, Nagashima M, Al-Fares A, Rodriguez-Gutierrez R, Gonzalez-Gonzalez J, Salcido-Montenegro A, Camacho-Ortiz A, Ulloa M, Hassan-Hanga F, Galadanci H, Gezawa A, Kabara H, Amole T, Kabir H, Haliru D, Ibrahim A, Asghar M, Syed M, Naqvi S, Zabolotskikh I, Zybin K, Sinkov S, Musaeva T, Alamoudi R, AlSharif H, Almazwaghi S, Elsakran M, Aid M, Darwich M, Hagag O, Ali S, rocacorba A, Supeña K, Juane E, Medina J, Baduria J, Amer M, Abdullah M, Bawazeer T, Kseibi E, Butt A, Khurshid S, Rabee M, Abujazar M, Alghunaim R, Abualkhair M, AlFirm A, Kseibi E, Khurshid S, Rabee M, Abujazar M, Alghunaim R, Arabi Y, Abdukahil S, Almazyad M, Alarifi M, Macarambon J, Bukhari A, Albahrani H, Asfina K, Aldossary K, Zdravkovic M, Todorovic Z, Popadic V, Klasnja S, Andrijevic A, Gavrilovic S, Carapic V, Kovacevic B, Bojicic J, Predrag S, Stojakov D, Ignjatovic D, Bojic S, Bobos M, Nenadic I, Zaric M, Djuric M, Djukic V, Teruel S, Martin B, Teruel S, Sili U, Bilgin H, Ay P, Gharpure V, Raheemi U, Dodd K, Goodmanson N, Hesse K, Bird P, Weinert C, Schoenrade N, Altaher A, Mayar E, Aronson M, Cooper T, Logan M, Miner B, Papo G, Siegal E, Runningen P, Barry S, Woll C, Wu G, Carrole E, Burke K, Mohammed M, Melamed R, Tierney D, Patel L, Raj V, Dawud B, Mazumder N, Sidebottom A, Guenther A, Krehbiel B, Schmitz N, Jepsen S, Sipsey L, Schulte A, Wunderlich W, Hoyt C, Raval A, Franks A, Irby K, Sanders R, Hefley G, Jarvis J, Kharbanda A, Jhajhria S, Fyffe Z, Capizzi S, Alicie B, Green M, Crockarell L, Drennan A, Dubuque K, Fambrough T, Gasaway N, Krantz B, Nebi P, Orga J, Serfass M, Simion A, Warren K, Wheeler C, Woolman C, Christie A, Ashley D, Adiga R, Moyer A, Verghese G, Newsome A, Forehand C, Bruning R, Jones T, Sabov M, Zaidi F, Tissavirasingham F, Malipeddi D, Mosier J, Lutrick K, Campbell B, Wilson C, Rivers P, Brinks J, Mongoh M, Gilson B, Armaignac D, Parris D, Zuniga M, Vargas I, Boronat V, Hutton A, Kaur N, Neupane P, Sadule-Rios N, Rojas L, Neupane A, Rivera P, Carlos C, Vincent G, Amin M, Schelle M, Steadham A, Howard C, McBride C, Abraham J, Garner O, Richards K, Collins K, Antony P, Mathew S, Danesh V, Dubrocq G, Davis A, Hammers M, McGahey I, Farris A, Priest E, Korsmo R, Fares L, Skiles K, Shor S, Burns K, Dowell C, Gonzales G, Flores M, Newman L, Wilk D, Ettlinger J, Bomar J, Darji H, Arroliga A, Arroliga A, Dowell C, Conzales G, Flores M, Newman L, Wilk D, Ettlinger J, Darji H, Bomar J, Khandhar P, Kring E, Banner-Goodspeed V, Bose S, Kelly L, Joseph M, McGourty M, Capers K, Hoenig B, Karamourtopoulos M, Law A, Kassis E, Walkey A, Waikar S, Garcia M, Colona M, Kibbelaar Z, Leong M, Wallman D, Soni K, Maccarone J, Gilman J, Devis Y, Chung J, Paracha M, Lumelsky D, DiLorenzo M, Abdurrahman N, Johnson S, Hersh A, Wachs S, Swigger B, Wachs S, Sattler L, Moulton M, Zammit K, Patrick J, Loeffler W, Maya R, Miller A, Anderson E, Nagy R, Inja R, Nawathe P, Pedraza I, Tsing J, Carr K, Chaudhary A, Guglielmino K, Tirupathi R, Tang A, Safi A, Green C, Newell J, Ihle R, Martin S, Davis E, Gist K, Sayed I, Brinton J, Strom L, Chiotos K, Blatz A, Lee G, Burnett R, Sydney G, Traynor D, Nauert K, Gonzalez A, Bagley M, Santpurkar A, Surani S, White J, Khan A, Dhahwal R, Cheruku S, Ahmed F, Deonarine C, Jones A, Shaikh M, Preston D, Chin J, Vachharajani V, Duggal A, Rajendram P, Mehkri O, Dugar S, Biehl M, Sacha G, Houltham S, King A, Ashok K, Poynter B, Beukemann M, Rice R, Gole S, Shaner V, Conjeevaram A, Ferrari M, Alappan N, Minear S, Hernandez-Montfort J, Nasim S, Sunderkrishnan R, Sahoo D, Milligan P, Gupta S, Koglin J, Gibson R, Johnson L, Preston F, Scott C, Nungester B, Byrne D, Schorr C, Grant K, Doktor K, Porto M, Kaplan O, Siegler J, Schonewald B, Woodford A, 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Neurologic Manifestations of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Hospitalized Patients During the First Year of the COVID-19 Pandemic. Critical Care Explorations 2022, 4: e0686. PMID: 35492258, PMCID: PMC9042584, DOI: 10.1097/cce.0000000000000686.Peer-Reviewed Original ResearchSerious neurologic manifestationsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionAcute respiratory syndrome coronavirus 2 infectionSyndrome coronavirus 2 infectionSARS-CoV-2 infectionMeningitis/encephalitisCoronavirus 2 infectionNeurologic manifestationsHospitalized patientsRisk factorsWorse outcomesSevere diseaseLaboratory-confirmed SARS-CoV-2 infectionMedian age 72 yearsHospital discharge statusVentilator-free daysCritical care interventionsProspective observational studyVascular risk factorsChronic medical conditionsAge 72 yearsCOVID-19 registryCOVID-19 infectionDisease Severity ScaleCare interventions