2024
Early‐ and Late‐Stage Auditory Processing of Speech Versus Non‐Speech Sounds in Children With Autism Spectrum Disorder: An ERP and Oscillatory Activity Study
Edgar E, McGuire K, Pelphrey K, Ventola P, van Noordt S, Crowley M. Early‐ and Late‐Stage Auditory Processing of Speech Versus Non‐Speech Sounds in Children With Autism Spectrum Disorder: An ERP and Oscillatory Activity Study. Developmental Psychobiology 2024, 66: e22552. PMID: 39508446, DOI: 10.1002/dev.22552.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderNon-speech soundsSpeech soundsTD childrenSpectrum disorderCortical activityResponses to speech soundsProcessing stagesSensitivity to speechAtypical auditory processingTheta phase coherenceAuditory speech processingP3a amplitudeAuditory speechIntra-individual variabilityDevelopment of cortical networksASD childrenCortical networksSpeech processingAuditory processingElectroencephalography sessionLanguage processingCortical responsesAutismSpeechThe relationship between gamma-band neural oscillations and language skills in youth with Autism Spectrum Disorder and their first-degree relatives
Arutiunian V, Santhosh M, Neuhaus E, Borland H, Tompkins C, Bernier R, Bookheimer S, Dapretto M, Gupta A, Jack A, Jeste S, McPartland J, Naples A, Van Horn J, Pelphrey K, Webb S. The relationship between gamma-band neural oscillations and language skills in youth with Autism Spectrum Disorder and their first-degree relatives. Molecular Autism 2024, 15: 19. PMID: 38711098, PMCID: PMC11075235, DOI: 10.1186/s13229-024-00598-1.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderElevated gamma powerLow language skillsGamma powerResponses to speech stimuliLanguage skillsLanguage functionFirst-degree relativesSpectrum disorderClinical Evaluation of Language FundamentalsCo-occurring language impairmentSpeech stimuliCortical gamma-band oscillationsHigh gamma powerSex-balanced sampleGamma-band oscillationsSample of participantsNonverbal IQLanguage impairmentASD participantsTD controlsNeural profilesAutism phenotypeTD groupLanguage FundamentalsConduction velocity, G-ratio, and extracellular water as microstructural characteristics of autism spectrum disorder
Newman B, Jacokes Z, Venkadesh S, Webb S, Kleinhans N, McPartland J, Druzgal T, Pelphrey K, Van Horn J, Consortium F. Conduction velocity, G-ratio, and extracellular water as microstructural characteristics of autism spectrum disorder. PLOS ONE 2024, 19: e0301964. PMID: 38630783, PMCID: PMC11023574, DOI: 10.1371/journal.pone.0301964.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSocial Communication QuestionnaireSpectrum disorderCharacteristics of autism spectrum disorderAssociated with higher scoresEtiology of autism spectrum disorderMagnetic resonance imagingNeurotypical participantsWhite matter skeletonCommunication QuestionnaireBehavioral functionsFunctional connectivityT1w/T2w ratioNeuronal differencesStructural connectivityAdolescent participantsHigher scoresConduction velocityCortexExtracellular waterDisordersResonance imagingDiffusion MRI techniques
2009
The Neural Development of an Abstract Concept of Number
Cantlon JF, Libertus ME, Pinel P, Dehaene S, Brannon EM, Pelphrey KA. The Neural Development of an Abstract Concept of Number. Journal Of Cognitive Neuroscience 2009, 21: 2217-2229. PMID: 19016605, PMCID: PMC2745480, DOI: 10.1162/jocn.2008.21159.Peer-Reviewed Original ResearchConceptsBrain mechanismsYears of lifeFunctional magnetic resonance imagingMagnetic resonance imagingInferior frontal cortexCore neural systemsFrontal cortexParietal cortexResonance imagingBrain regionsPrimate neurophysiologyDifferent notation systemsYoung childrenNeural developmentAdultsLiterate adultsCortexChildrenNumerical tasksNeural systemsAbstract conceptsAdditional supportAdult recruitsGreater degreeNumerical representationBrain Regions for Perceiving and Reasoning About Other People in School‐Aged Children
Saxe RR, Whitfield‐Gabrieli S, Scholz J, Pelphrey KA. Brain Regions for Perceiving and Reasoning About Other People in School‐Aged Children. Child Development 2009, 80: 1197-1209. PMID: 19630902, DOI: 10.1111/j.1467-8624.2009.01325.x.Peer-Reviewed Original ResearchConceptsTemporo-parietal junctionPosterior superior temporal sulcusRight temporo-parietal junctionSuperior temporal sulcusMedial prefrontal cortexSchool-Aged ChildrenBiological motionTemporal sulcusCharacters' thoughtsPrefrontal cortexPeople's thoughtsMental factsPosterior cingulateBrain regionsCortical regionsYoung childrenOlder childrenSame storyThoughtPhysical contextResponse selectivityChildrenPeoplePerceivingCingulateAction Understanding in the Superior Temporal Sulcus Region
Vander Wyk BC, Hudac CM, Carter EJ, Sobel DM, Pelphrey KA. Action Understanding in the Superior Temporal Sulcus Region. Psychological Science 2009, 20: 771-777. PMID: 19422619, PMCID: PMC2849148, DOI: 10.1111/j.1467-9280.2009.02359.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttentionBrain MappingChoice BehaviorColor PerceptionConcept FormationDominance, CerebralEmotionsFemaleHumansImage Processing, Computer-AssistedIntentionMagnetic Resonance ImagingMaleMotion PerceptionOxygenPattern Recognition, VisualPersonal Construct TheoryPsychomotor PerformanceSocial PerceptionTemporal LobeYoung AdultConceptsSuperior temporal sulcus regionEmotional expressionSTS regionPosterior superior temporal sulcus regionSulcus regionFunctional magnetic resonancePosterior STSAction understandingBiological motionEmotional contextNegative emotionsNegative regardPositive regardPerson's motionSocial actCongruentParticipantsIntentionEmotionsObjectsCongruencyPerceptionActionActressMagnetic resonance
2008
Developmental changes in category-specific brain responses to numbers and letters in a working memory task
Libertus ME, Brannon EM, Pelphrey KA. Developmental changes in category-specific brain responses to numbers and letters in a working memory task. NeuroImage 2008, 44: 1404-1414. PMID: 19027079, PMCID: PMC2659412, DOI: 10.1016/j.neuroimage.2008.10.027.Peer-Reviewed Original ResearchConceptsCategory-specific activationFunctional magnetic resonance imagingWM taskMemory taskBehavioral performanceBrain activityBrain regionsCategory-specific dissociationsLateral fusiform gyrusOccipital-temporal cortexBrain activity patternsEight-year-old childrenFace stimuliWM conditionCognitive abilitiesSemantic processingLanguage abilityLetter conditionFMRI resultsFusiform gyrusAbstract processingIntraparietal sulcusBrain responsesDigit conditionLinguistic abilitiesPhysiology and functioning: Parents’ vagal tone, emotion socialization, and children’s emotion knowledge
Perlman SB, Camras LA, Pelphrey KA. Physiology and functioning: Parents’ vagal tone, emotion socialization, and children’s emotion knowledge. Journal Of Experimental Child Psychology 2008, 100: 308-315. PMID: 18486947, DOI: 10.1016/j.jecp.2008.03.007.Peer-Reviewed Original ResearchConceptsChildren's emotion knowledgeEmotion knowledgeSocialization behaviorsEmotion socialization behaviorsEmotional facial expressionsFamily emotional expressivenessVagal toneEmotion socializationEmotional expressivenessEmotional developmentCardiac vagal toneFacial expressionsSocialization variablesLaboratory sessionsParentsPhysiological regulationToneChildrenFunctioningBehaviorSocializationSessionsExpressivenessKnowledgeFindings