Unsupervised Dimensionality Reduction Techniques for the Assessment of ASD Biomarkers.
Jacokes Z, Adoremos I, Hussain A, Newman B, Pelphrey K, Van Horn J. Unsupervised Dimensionality Reduction Techniques for the Assessment of ASD Biomarkers. Biocomputing 2025, 30: 614-630. PMID: 39670400.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderNeural basisDevelopmental disabilitiesCognitive traitsDiagnostic disparitiesSpectrum disorderNeuroimaging techniquesASD biomarkersSex differencesSocial functioningASD researchEffects of gene expressionNeuronal microstructureTailored interventionsBiological influencesGenetic interactionsGene expressionPhenotypic heterogeneityAutismCognitionPrincipal component analysis