Centralspindlin proteins Pavarotti and Tumbleweed along with WASH regulate nuclear envelope budding
Davidson K, Nakamura M, Verboon J, Parkhurst S. Centralspindlin proteins Pavarotti and Tumbleweed along with WASH regulate nuclear envelope budding. Journal Of Cell Biology 2023, 222: e202211074. PMID: 37163553, PMCID: PMC10174194, DOI: 10.1083/jcb.202211074.Peer-Reviewed Original ResearchConceptsNuclear envelope buddingActin nucleation activityNuclear export pathwayNE buddingExport pathwayWiskott-Aldrich syndrome proteinProtein quality controlActin-bundling activityNew molecular componentsCargo recruitmentSyndrome proteinRegulatory complexMitochondrial integritySynapse developmentCell differentiationStructural roleMolecular componentsNuclear washesLarge cargoBuddingPavarottiBudsMachineryTumbleweedNew entry point