Therapeutic efficacy of Ac-DMQD-CHO, a caspase 3 inhibitor, for rat spinal cord injury
Akdemir O, Berksoy I, Karaoğlan A, Barut Ş, Bilguvar K, Çirakoğlu B, Şahan E, Çolak A. Therapeutic efficacy of Ac-DMQD-CHO, a caspase 3 inhibitor, for rat spinal cord injury. Journal Of Clinical Neuroscience 2008, 15: 672-678. PMID: 18378144, DOI: 10.1016/j.jocn.2007.06.014.Peer-Reviewed Original ResearchConceptsSpinal cord injuryCord injuryGroup 2Therapeutic efficacyRat spinal cord injuryDiffuse hemorrhagic necrosisSpinal cord traumaGroup 3 ratsPolymorphonuclear leukocyte infiltrationCaspase-3 inhibitorCord traumaFunctional recoveryLeukocyte infiltrationLight microscopy examinationHemorrhagic necrosisNeurologic performanceFunctional outcomeSpinal cordRat modelTraumatic injuryVascular thrombiTreatment responseGroup 3InjuryThoracic regionNeuroprotective effects of Ac.YVAD.cmk on experimental spinal cord injury in rats
Karaoğlan A, Kaya E, Akdemir O, Sağmanligil A, Bilguvar K, Çirakoğlu B, Şahan E, Erdoğan N, Barut Ş, Çolak A. Neuroprotective effects of Ac.YVAD.cmk on experimental spinal cord injury in rats. World Neurosurgery 2008, 69: 561-567. PMID: 18262241, DOI: 10.1016/j.surneu.2007.03.041.Peer-Reviewed Original Research