2023
Cellular activation pathways and interaction networks in vascularized composite allotransplantation
Knoedler L, Knoedler S, Panayi A, Lee C, Sadigh S, Huelsboemer L, Stoegner V, Schroeter A, Kern B, Mookerjee V, Lian C, Tullius S, Murphy G, Pomahac B, Kauke-Navarro M. Cellular activation pathways and interaction networks in vascularized composite allotransplantation. Frontiers In Immunology 2023, 14: 1179355. PMID: 37266446, PMCID: PMC10230044, DOI: 10.3389/fimmu.2023.1179355.Peer-Reviewed Original ResearchConceptsVascularized Composite AllotransplantationComposite allotransplantationRecipient-derived lymphocytesTreatment of patientsCellular activation pathwaysMultidrug immunosuppressionVCA graftsVCA patientsVCA rejectionGraft rejectionDevastating injuriesClinical managementNovel therapiesReconstructive surgeryLimb lossRejection responseFacial disfigurementAllotransplantationPatientsGraftActivation pathwayTissue cellsDifferent cell typesTissue typesCell types
2021
Dynamic Maxillary Sinus Changes of Facial Vascularized Composite Allotransplants.
Kauke M, Safi AF, Palmer WJ, Kollar B, Nelms L, Tchiloemba B, Haug V, Pomahac B. Dynamic Maxillary Sinus Changes of Facial Vascularized Composite Allotransplants. Plastic & Reconstructive Surgery 2021, 147: 722-727. PMID: 33620943, DOI: 10.1097/prs.0000000000007673.Peer-Reviewed Original ResearchConceptsMaxillary sinusFace transplant recipientsTransplant recipientsAllograft rejectionTissue changesBiopsy-proven allograft rejectionDiagnosis of rejectionMedication side effectsMaxillary sinus mucosaIndividualized treatment strategiesTissue allograft rejectionVascularized composite allotransplantsFace transplant patientsDynamic tissue changesRadiologic biomarkersRejection gradeTransplant patientsMucosal swellingSinonasal tractSinus changesSinus mucosaClinical managementTomographic scanPathologic changesTreatment strategies