2023
The common trisomy syndromes, their cardiac implications, and ethical considerations in care
Kosiv K, Mercurio M, Carey J. The common trisomy syndromes, their cardiac implications, and ethical considerations in care. Current Opinion In Pediatrics 2023, 35: 531-537. PMID: 37551160, DOI: 10.1097/mop.0000000000001278.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseCardiac surgeryHeart diseaseTrisomy 13Trisomy 21Cardiac surgical repairCongenital heart surgeryCardiac implicationsPulmonary hypertensionSurgical repairSurgical interventionPatient populationHeart surgerySurgeryTreatment planCommon trisomiesDiseaseTrisomyCareSurvivalHypertensionMorbidityPatientsManagementEthical controversies
2022
Longitudinal Assessment of Global and Regional Left Ventricular Strain in Patients with Multisystem Inflammatory Syndrome in Children (MIS-C)
He M, Leone DM, Frye R, Ferdman DJ, Shabanova V, Kosiv KA, Sugeng L, Faherty E, Karnik R. Longitudinal Assessment of Global and Regional Left Ventricular Strain in Patients with Multisystem Inflammatory Syndrome in Children (MIS-C). Pediatric Cardiology 2022, 43: 844-854. PMID: 34993558, PMCID: PMC8739007, DOI: 10.1007/s00246-021-02796-7.Peer-Reviewed Original ResearchConceptsMIS-C patientsAcute phaseChronic phaseInflammatory syndromeTwo-dimensional speckle tracking echocardiographySubclinical myocardial injuryCircumferential strainMultisystem inflammatory syndromeLeft ventricular dysfunctionSingle-institution reviewSpeckle tracking echocardiographyTwo-dimensional echocardiographyCoronavirus disease 2019Future adverse eventsVentricular function parametersBasal anterolateral segmentMean GCSVentricular dysfunctionAdverse eventsFractional shorteningSignificant sequelaeVentricular strainMyocardial dysfunctionGlobal longitudinalMyocardial injury
2021
Fetal cerebrovascular impedance is reduced in left congenital diaphragmatic hernia
Kosiv K, Moon‐Grady A, Hogan W, Keller R, Rapoport R, Rogers E, Feldstein V, Lee H, Peyvandi S. Fetal cerebrovascular impedance is reduced in left congenital diaphragmatic hernia. Ultrasound In Obstetrics And Gynecology 2021, 57: 386-391. PMID: 32068925, PMCID: PMC7431368, DOI: 10.1002/uog.21992.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PhysiologicalCardiography, ImpedanceCase-Control StudiesCerebrovascular CirculationEchocardiographyElectric ImpedanceFemaleFetal DevelopmentFetusFunctional LateralityGestational AgeHernias, Diaphragmatic, CongenitalHumansMiddle Cerebral ArteryNeurodevelopmental DisordersPregnancyPulsatile FlowUltrasonography, PrenatalUmbilical ArteriesConceptsLeft ventricular cardiac outputLeft-sided CDHCongenital diaphragmatic herniaMCA-PI Z-scoreMCA-PICerebral blood flowCardiac outputRight-sided CDHPulsatility indexHead circumferenceBiparietal diameterCDH survivorsBlood flowSmall left-sided cardiac structuresMiddle cerebral artery pulsatility indexRight-sided congenital diaphragmatic herniaLeft-sided congenital diaphragmatic herniaLeft-sided cardiac structuresPercentage of COCerebral artery pulsatility indexGestational age-matched controlsZ-scoreMCA PI valuesArtery pulsatility indexSignificant mass effectA validated model for prediction of survival to 6 months in patients with trisomy 13 and 18
Kosiv KA, Long J, Lee HC, Collins RT. A validated model for prediction of survival to 6 months in patients with trisomy 13 and 18. American Journal Of Medical Genetics Part A 2021, 185: 806-813. PMID: 33403783, DOI: 10.1002/ajmg.a.62044.Peer-Reviewed Original ResearchConceptsCongenital heart surgeryC-statisticMonths of ageTrisomy 13Heart surgeryCalifornia Perinatal Quality Care CollaborativePediatric Health Information System databaseHealth Information System databaseStatewide Health PlanningModel c-statisticCongenital heart diseasePrediction of survivalDay of deathParenteral nutritionCardiac surgeryMechanical ventilationStudy cohortValidation cohortCare CollaborativeHeart diseaseInformation System databaseInpatient dataCalifornia OfficeHealth planningSurgery
2018
Author Response
Collins RT, Kosiv K, Bai S, Gossett J. Author Response. Pediatrics 2018, 141: e20180400b. PMID: 29712760, DOI: 10.1542/peds.2018-0400b.Peer-Reviewed Original Research
2017
Congenital Heart Surgery on In-Hospital Mortality in Trisomy 13 and 18
Kosiv KA, Gossett JM, Bai S, Collins RT. Congenital Heart Surgery on In-Hospital Mortality in Trisomy 13 and 18. Pediatrics 2017, 140: e20170772. PMID: 29046387, DOI: 10.1542/peds.2017-0772.Peer-Reviewed Original ResearchConceptsCongenital heart surgeryCongenital heart diseaseHospital mortalityHeart surgeryPediatric Health Information System databaseTrisomy 13Health Information System databaseIn-Hospital MortalityLength of stayDays of ageHospital readmissionSurgical repairStudy cohortFemale sexHeart diseaseInformation System databaseMost centersTrisomy 18Select casesInfantsMortalityOlder ageSurgerySystem databaseT18