2019
Receptor tyrosine kinases (RTKs) consociate in regulatory clusters in Alzheimer’s disease and type 2 diabetes
Majumder P, Roy K, Bagh S, Mukhopadhyay D. Receptor tyrosine kinases (RTKs) consociate in regulatory clusters in Alzheimer’s disease and type 2 diabetes. Molecular And Cellular Biochemistry 2019, 459: 171-182. PMID: 31154588, DOI: 10.1007/s11010-019-03560-5.Peer-Reviewed Original ResearchConceptsType 2 diabetesAlzheimer's diseaseReceptor tyrosine kinasesPost-mortem Alzheimer's diseaseFuture therapeutic developmentInsulin resistanceDisease typeActivity statusDiseaseCommon hallmarkTherapeutic developmentDefinitive roleDiabetesOne-thirdTyrosine kinaseCell modelSimilar regulatory mechanismsT2D.Regulatory mechanisms
2013
Differential Expression of Neuroblastoma Cellular Proteome due to AICD Overexpression
Chakrabarti A, Roy K, Mukhopadhyay D. Differential Expression of Neuroblastoma Cellular Proteome due to AICD Overexpression. Journal Of Alzheimer's Disease 2013, 38: 845-855. PMID: 24081375, DOI: 10.3233/jad-130695.Peer-Reviewed Original ResearchConceptsAmyloid-β protein precursor intracellular domainCell linesProteomic expression patternsDifferent functional classesCellular proteomeCytoskeletal dynamicsProtein foldingIntracellular domainExpression patternsBiological processesBiological pathwaysMALDI-MS identificationNormal proteomeDifferential expressionSHSY5Y cell lineNeuroblastoma cell linesKey playersProteomeAlzheimer's diseaseProtein overloadArtifactual consequenceProteinAD-like conditionsAD phenotypePathophysiological effects