2018
Morphogenesis and Compartmentalization of the Intestinal Crypt
Sumigray KD, Terwilliger M, Lechler T. Morphogenesis and Compartmentalization of the Intestinal Crypt. Developmental Cell 2018, 45: 183-197.e5. PMID: 29689194, PMCID: PMC5987226, DOI: 10.1016/j.devcel.2018.03.024.Peer-Reviewed Original ResearchConceptsRac1 null miceAdult mammalian intestineCell shape changesProgenitor cellsStem cell nicheGene networksCrypt morphogenesisCrypt progenitor cellsEssential regulatorMammalian intestineCell nicheGenetic analysisUnexpected roleApical constrictionNiche formationHemidesmosomal adhesionCrypt developmentTissue architectureMouse cryptsMorphogenesisAbsorptive villiNull miceIntestinal cryptsQuantitative morphometricsShape changes
2010
Dissecting cell adhesion cross-talk with micropatterns
Sumigray KD, Lechler T. Dissecting cell adhesion cross-talk with micropatterns. Proceedings Of The National Academy Of Sciences Of The United States Of America 2010, 107: 13199-13200. PMID: 20639470, PMCID: PMC2922164, DOI: 10.1073/pnas.1008253107.Peer-Reviewed Original Research