2009
Hospital Arrival Time and Intravenous t-PA Use in US Academic Medical Centers, 2001–2004
Lichtman JH, Watanabe E, Allen NB, Jones SB, Dostal J, Goldstein LB. Hospital Arrival Time and Intravenous t-PA Use in US Academic Medical Centers, 2001–2004. Stroke 2009, 40: 3845-3850. PMID: 19797697, DOI: 10.1161/strokeaha.109.562660.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAgedAged, 80 and overBlack or African AmericanBrain IschemiaEmergency Medical ServicesEmergency Service, HospitalFemaleHealth Services AccessibilityHumansInjections, IntravenousIntracranial ThrombosisMaleMiddle AgedQuality of Health CareSeverity of Illness IndexStrokeThrombolytic TherapyTime FactorsTissue Plasminogen ActivatorTransportation of PatientsUnited StatesWhite PeopleConceptsIschemic stroke patientsSymptom onsetT-PA useStroke patientsHospital arrivalIntravenous tissue-type plasminogen activatorConsecutive ischemic stroke patientsEarly hospital arrivalPercentage of patientsUS academic centersHospital arrival timeRisk-adjusted analysisMultivariate logistic regressionCare-seeking behaviorAcademic medical centerTissue-type plasminogen activatorClinical characteristicsSevere strokePatient characteristicsBlack patientsEmergency departmentMedical recordsHospital careMedical CenterLower odds
2001
Utilization of Intravenous Tissue-Type Plasminogen Activator for Ischemic Stroke at Academic Medical Centers
Johnston S, Fung L, Gillum L, Smith W, Brass L, Lichtman J, Brown A. Utilization of Intravenous Tissue-Type Plasminogen Activator for Ischemic Stroke at Academic Medical Centers. Stroke 2001, 32: 1061-1068. PMID: 11340210, DOI: 10.1161/01.str.32.5.1061.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAgedBlack or African AmericanBrain IschemiaCohort StudiesContraindicationsDatabases, FactualDrug Utilization ReviewFemaleFibrinolytic AgentsHumansLogistic ModelsMaleMiddle AgedPatient DischargeStrokeThrombolytic TherapyTissue Plasminogen ActivatorUnited StatesWhite PeopleConceptsAcademic medical centerTissue-type plasminogen activatorIschemic strokeMedical CenterIntravenous tissue-type plasminogen activatorConsecutive ischemic stroke casesAfrican AmericansPlasminogen activatorIschemic stroke patientsUS academic medical centersMultivariable logistic regressionMedical insuranceIschemic stroke casesMedical insurance typePrivate medical insuranceTPA useStroke severityStroke patientsStroke casesMedical historyInsurance typeMedical recordsUnivariate analysisContraindicationsLogistic regression
2000
Intracranial Hemorrhage Associated With Thrombolytic Therapy for Elderly Patients With Acute Myocardial Infarction
Brass L, Lichtman J, Wang Y, Gurwitz J, Radford M, Krumholz H. Intracranial Hemorrhage Associated With Thrombolytic Therapy for Elderly Patients With Acute Myocardial Infarction. Stroke 2000, 31: 1802-1811. PMID: 10926938, DOI: 10.1161/01.str.31.8.1802.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionThrombolytic therapyIntracranial hemorrhageMyocardial infarctionElderly patientsIntracranial Hemorrhage AssociatedRetrospective cohort studyRisk stratification scaleMain outcome measuresAcute care hospitalsTissue plasminogen activatorExcessive anticoagulationPrior strokeCohort studyOlder patientsBlood pressureHemorrhage AssociatedIndependent predictorsMedical chartsSerious complicationsMedian weightAlternate therapyBlack racePrincipal diagnosisMedicare patients