2006
The Interactions of Polarographic Measurements of Oxygen Tension and Histological Grade in Human Glioma
Lally BE, Rockwell S, Fischer DB, Collingridge DR, Piepmeier JM, Knisely JP. The Interactions of Polarographic Measurements of Oxygen Tension and Histological Grade in Human Glioma. The Cancer Journal 2006, 12: 461-466. PMID: 17207315, DOI: 10.1097/00130404-200611000-00005.Peer-Reviewed Original ResearchConceptsHistological gradeHigh-grade gliomasLow-grade gliomasTumor oxygen tensionUnivariate analysisOxygen tensionGrade gliomasSignificant independent prognostic indicatorExtent of surgeryType of anesthesiaIndependent prognostic indicatorEppendorf pO2 histographTissue oxygen tensionNormal brain tissueImplications of hypoxiaOverall survivalProspective trialPatient ageEntire cohortPrognostic indicatorPatient genderPoor survivalMedian pO2PatientsPO2 histograph
1996
Variations in the natural history and survival of patients with supratentorial low-grade astrocytomas.
Piepmeier J, Susan Christopher R, Spencer D, Byrne T, Kim J, Knisel J, Lacy J, Tsukerman L, Makuch R. Variations in the natural history and survival of patients with supratentorial low-grade astrocytomas. Neurosurgery 1996, 38: 872-8; discussion 878-9. PMID: 8727811, DOI: 10.1097/00006123-199605000-00002.Peer-Reviewed Original ResearchConceptsLow-grade astrocytomasGross total resectionChronic epilepsySupratentorial low-grade astrocytomasNatural historyGross total tumor resectionImmediate postoperative radiotherapyExtent of surgerySurvival of patientsTen-year survivalPopulation of patientsUse of radiotherapyRisk of recurrenceHigh-grade lesionsLength of survivalMore malignant tumorsTypes of symptomsAggressive surgeryPostoperative radiotherapyPreoperative symptomsConsecutive patientsBetter prognosisTumor recurrenceTumor resectionMalignant tumors