Quantifying Mycobacterium tuberculosis Transmission Dynamics Across Global Settings: A Systematic Analysis
Smith J, Cohen T, Dowdy D, Shrestha S, Gandhi NR, Hill AN. Quantifying Mycobacterium tuberculosis Transmission Dynamics Across Global Settings: A Systematic Analysis. American Journal Of Epidemiology 2022, 192: 133-145. PMID: 36227246, PMCID: PMC10144641, DOI: 10.1093/aje/kwac181.Peer-Reviewed Original ResearchConceptsTB transmissionOngoing TB transmissionMinority of casesTuberculosis transmission dynamicsTB controlTuberculosis transmissionSecondary casesSources of heterogeneityInclusion criteriaSurveillance studyTransmission clustersInitial searchTransmission dynamicsWhole-genome sequencingPopulation levelSettingModel-based Analysis of Tuberculosis Genotype Clusters in the United States Reveals High Degree of Heterogeneity in Transmission and State-level Differences Across California, Florida, New York, and Texas
Shrestha S, Winglee K, Hill A, Shaw T, Smith J, Kammerer JS, Silk BJ, Marks S, Dowdy D. Model-based Analysis of Tuberculosis Genotype Clusters in the United States Reveals High Degree of Heterogeneity in Transmission and State-level Differences Across California, Florida, New York, and Texas. Clinical Infectious Diseases 2022, 75: 1433-1441. PMID: 35143641, PMCID: PMC9412192, DOI: 10.1093/cid/ciac121.Peer-Reviewed Original ResearchConceptsTB casesTB transmissionKey public health priorityPublic health priorityMechanistic transmission modelsTB incidenceTuberculosis transmissionSecondary casesHealth priorityInfectious casesTransmission clustersDisease controlMean numberR0 estimatesUnited StatesWhole-genome sequencingSame countyGenotype clustersState-level differencesSecondary transmissionCasesIncidence