Regulation of interleukin-8 via an airway epithelial signaling cascade
Nakanaga T, Nadel JA, Ueki IF, Koff JL, Shao MX. Regulation of interleukin-8 via an airway epithelial signaling cascade. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2007, 292: l1289-l1296. PMID: 17220369, DOI: 10.1152/ajplung.00356.2006.Peer-Reviewed Original ResearchConceptsIL-8 productionIL-8 expressionHuman airway epithelial NCI-H292 cellsEGF receptorNeutrophil chemoattractant interleukinEpithelial cellsNCI-H292 cellsAirway epithelial cellsModel inflammatory stimulusNegative bacterial lipopolysaccharideDual oxidase 1MAP kinases ERK1/2IL-8Tumor necrosisInterleukin-8Immune organsInflammatory stimuliMucin productionHuman airwaysAirwayEpithelial defenseTACE activationBacterial infectionsHost defenseConverting enzyme