2013
Vesicular Stomatitis Virus Variants Selectively Infect and Kill Human Melanomas but Not Normal Melanocytes
Wollmann G, Davis JN, Bosenberg MW, van den Pol AN. Vesicular Stomatitis Virus Variants Selectively Infect and Kill Human Melanomas but Not Normal Melanocytes. Journal Of Virology 2013, 87: 6644-6659. PMID: 23552414, PMCID: PMC3676084, DOI: 10.1128/jvi.03311-12.Peer-Reviewed Original ResearchConceptsVesicular stomatitis virusReplication-competent vesicular stomatitis virusMetastatic malignant melanomaRecombinant vesicular stomatitis virusMouse melanoma modelHuman melanoma samplesGene mutation statusVSV-CT9Low viral concentrationsMelanoma typesMalignant melanomaSCID miceViral oncolysisMelanoma xenograftsViral infectionMelanoma modelMutation statusMalignant transformationHuman melanomaInfectionMelanomaVirus variantsComplete protectionMelanoma samplesGene mutations
1998
Matrilineal inheritance of complex I dysfunction in a multigenerational Parkinson's disease family
Swerdlow R, Parks J, Davis J, Cassarino D, Trimmer P, Currie L, Dougherty J, Bridges W, Bennett J, Wooten G, Parker W. Matrilineal inheritance of complex I dysfunction in a multigenerational Parkinson's disease family. Annals Of Neurology 1998, 44: 873-881. PMID: 9851431, DOI: 10.1002/ana.410440605.Peer-Reviewed Original ResearchConceptsCybrid linesMaternal descendantsComplex I dysfunctionInherited mtDNA mutationsCybrid cell linesIncreased reactive oxygen species productionReactive oxygen species productionComplex I activityMitochondrial DNAMtDNA mutationsHuman neuroblastoma cellsFamily membersMitochondrial morphologyMtDNACytoplasmic hybridsPaternal descendantsOxygen species productionCybridsGenetic lesionsMatrilineal inheritanceMaternal lineMultiple membersI activityNeuroblastoma cellsEnzyme activity