2021
Diversity in responses to oncolytic Lassa-vesicular stomatitis virus in patient-derived glioblastoma cells
Kim T, Puckett S, Zhang K, Herpai D, Ornelles D, Davis J, van den Pol A, Debinski W, Lyles D. Diversity in responses to oncolytic Lassa-vesicular stomatitis virus in patient-derived glioblastoma cells. Molecular Therapy Oncology 2021, 22: 232-244. PMID: 34514102, PMCID: PMC8424128, DOI: 10.1016/j.omto.2021.06.003.Peer-Reviewed Original ResearchGreen fluorescent proteinGlioblastoma cell linesCell deathCell linesLevels of viral gene expressionViral gene expressionExpression of interferon-stimulated genesLassa virus glycoproteinInterferon-stimulated genesRNA-seqIndividual cell linesLow passagePatient-derived cellsPatient-derived glioblastoma cellsExpressing green fluorescent proteinRNA sequencingInterferon pathway activationFluorescent proteinGene expressionGlioma stem-like cellsStem-like cellsStomatitis virusCell viability assayBrain Tumor CenterSusceptible cells
2017
Chikungunya, Influenza, Nipah, and Semliki Forest Chimeric Viruses with Vesicular Stomatitis Virus: Actions in the Brain
van den Pol AN, Mao G, Chattopadhyay A, Rose JK, Davis JN. Chikungunya, Influenza, Nipah, and Semliki Forest Chimeric Viruses with Vesicular Stomatitis Virus: Actions in the Brain. Journal Of Virology 2017, 91: 10.1128/jvi.02154-16. PMID: 28077641, PMCID: PMC5331823, DOI: 10.1128/jvi.02154-16.Peer-Reviewed Original ResearchConceptsAdult mouse brainVesicular stomatitis virusVSV glycoprotein (G) geneAdult brainChimeric virusesOncolytic virusesVirus-like vesiclesChimeric vesicular stomatitis virusMouse brainSemliki Forest virusStomatitis virusPostnatal day 14 miceHealthy adult mouse brainRecombinant vesicular stomatitis virusKey immune mechanismsType I interferon responseG glycoproteinI interferon responseInterferon-stimulated genesDay 14 miceInfluenza H5N1 virusGlycoprotein geneNeurotropic natureIntranasal inoculationWild-type vesicular stomatitis virus