Featured Publications
Transcatheter Aortic Valve Replacement in Low-risk Patients With Bicuspid Aortic Valve Stenosis
Forrest JK, Ramlawi B, Deeb GM, Zahr F, Song HK, Kleiman NS, Chetcuti SJ, Michelena HI, Mangi AA, Skiles JA, Huang J, Popma JJ, Reardon MJ. Transcatheter Aortic Valve Replacement in Low-risk Patients With Bicuspid Aortic Valve Stenosis. JAMA Cardiology 2020, 6: 50-57. PMID: 33031491, PMCID: PMC7542521, DOI: 10.1001/jamacardio.2020.4738.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementBicuspid aortic valve stenosisAortic valve replacementAortic valve stenosisLow-risk patientsDevice success rateValve replacementValve stenosisCause mortalityRandomized trialsAmerican Heart Association/American CollegeSevere bicuspid aortic valve stenosisHigh device success rateLow surgical risk patientsPrespecified primary end pointPrimary efficacy end pointEnd pointBicuspid aortic stenosisMean AV gradientThoracic Surgeons scoreEfficacy end pointPrimary end pointLow surgical riskMild paravalvular leakNew permanent pacemaker
2016
Transcatheter Aortic Valve Replacement Versus Surgery in Women at High Risk for Surgical Aortic Valve Replacement (from the CoreValve US High Risk Pivotal Trial)
Skelding KA, Yakubov SJ, Kleiman NS, Reardon MJ, Adams DH, Huang J, Forrest JK, Popma JJ. Transcatheter Aortic Valve Replacement Versus Surgery in Women at High Risk for Surgical Aortic Valve Replacement (from the CoreValve US High Risk Pivotal Trial). The American Journal Of Cardiology 2016, 118: 560-566. PMID: 27381665, DOI: 10.1016/j.amjcard.2016.05.051.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementSevere aortic stenosisValve replacementCause mortalityAortic stenosisHigh riskKansas City Cardiomyopathy Questionnaire summary scoreTAVR-treated patientsSelf-expanding valvesMajor stroke rateSelf-expanding prosthesisQuality of lifeSAVR groupSAVR patientsVersus SurgeryTAVR patientsBaseline characteristicsMajor strokeDiabetes mellitusStroke rateSurvival advantageSummary scoresPatientsTranscatheter Aortic Valve Replacement in Women Versus Men (from the US CoreValve Trials)
Forrest JK, Adams DH, Popma JJ, Reardon MJ, Deeb GM, Yakubov SJ, Hermiller JB, Huang J, Skelding KA, Lansky A. Transcatheter Aortic Valve Replacement in Women Versus Men (from the US CoreValve Trials). The American Journal Of Cardiology 2016, 118: 396-402. PMID: 27346591, DOI: 10.1016/j.amjcard.2016.05.013.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic Valve StenosisCause of DeathComorbidityFemaleFrail ElderlyHumansIncidenceMaleMortalityPostoperative ComplicationsPostoperative HemorrhageSeverity of Illness IndexSex FactorsStrokeTranscatheter Aortic Valve ReplacementTreatment OutcomeVentricular Dysfunction, LeftConceptsTranscatheter aortic valve replacementAortic valve replacementCoreValve prosthesisValve replacementSevere symptomatic aortic stenosisSurgical aortic valve replacementLeft ventricular systolic functionWomen Versus MenMajor vascular complicationsSymptomatic aortic stenosisIncidence of strokeProcedure-related complicationsVentricular systolic functionCoronary artery diseaseLife-threatening bleedsSignificant baseline differencesGender-related differencesCause mortalityVascular complicationsBaseline characteristicsPatient characteristicsPrevious strokeSystolic functionAortic stenosisArtery disease